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Sandramoderator
Member since Feb-27-07
801 posts
Jan-01-09, 10:57 PM (PST)
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"My Supplements with Links"
 
LAST EDITED ON Feb-10-09 AT 04:03 AM (PST) by admin (admin)
 
Sandra asked me to modify her post. She is no longer taking DLPA (DL-Phenylalanine) with LDN (Low Dose Naltrexone) because she discovered that DLPA is a precursor to tyrosine. DCA inhibits the metabolism of tyrosine, so anyone using DCA should try to limit their intake of tyrosine to prevent toxicity. See discussion on this thread: https://thedcasite.com/dcaforum/DCForumID4/83.html

Decided to update my list of supplements - I've dropped a number of things, not because I think they are necessarily ineffective, but mostly because after 3 years it is difficult to swallow that many pills consistently

Here's a link to my previous list that included dosages:
https://thedcasite.com/cgi/dcboard.cgi?az=read_count&om=32&forum=DCForumID10&viewmode=threaded


Here is the revised list. I actually use more AOR products, but LEF is easy to buy online which is why I used their product links where possible:

Mitochondrial Energy Optimizer contains -
Acetyl-L-carnitine and carnosine
B-6
Benfotiamine (bioavailable B-1)
Luteolin
R+ Lipoic Acid
http://www.lef.org/Vitamins-Supplements/Item01268/Mitochondrial-Energy-Optimizer.html

Black Cumin Seed Oil (topically and internally)
http://www.drkowalski.com/blseoi8ozamh.html
http://www.scielo.br/pdf/bjmbr/v40n6/6124.pdf
http://www.ncbi.nlm.nih.gov/pubmed/16819096?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed
http://www.ncbi.nlm.nih.gov/pubmed/12724920?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Vitamin B-12 Complex with folic acid, (SUBLINGUAL IS IMPORTANT!) either of these
http://www.nowfoods.com/Products/ProductsbyCategory/Category/M011375.htm?cat=Vitamins%2cAmino%20Acids
http://www.lef.org/Vitamins-Supplements/Item00361/Vitamin-B12.html
(must add additional folic acid with the LEF brand B-12)

Curcumin
http://www.lef.org/Vitamins-Supplements/Item00912/Super-Curcumin-with-Bioperine.html

DCA 10-12 mg/kg/day, weekends off

DHA and Omega 3
http://www.nordicnaturals.com/en/General_Public/BUY_NOW!/98/?ProdID=1413
http://www.nordicnaturals.com/en/General_Public/BUY_NOW!/98/?ProdID=1427

Vitamin D - 8000 IU's in winter
http://www.lef.org/Vitamins-Supplements/Item00864/Liquid-Emulsified-Vitamin-D3.html

Vitamin E (VES) d-alpha tocopheryl succinate THIS FORM ONLY because it is 'redox silent'!
http://us.naturalfactors.com/search.asp?mode=cat&cat=25 (code 1436)

EGCG (either of these)
http://www.newcancerresearch.com/about.htm
http://www.lef.org/Vitamins-Supplements/Item00953/Mega-Green-Tea-Extract-lightly-caffeinated.html

HMR Lignans
http://www.swansonvitamins.com/SWU334/ItemDetail
http://www.hmrlignan.com/html/Swanson.pdf
http://www.hmrlignan.com/html/breast.htm

I3C - do not take with antacids, H2-receptor blockers (e.g. Zantac®), or proton-pump inhibitors (e.g. Nexium®)
http://www.lef.org/Vitamins-Supplements/Item00969/Dual-Action-Cruciferous-Vegetable-Extract-with-Resveratrol-Cats-Claw.html
https://thedcasite.com/Resistance/Resistance.html#I3C

ImmuneFX
http://www.purica.com/immune_fx.htm

Iodoral for iodine
(I take 37.5 to 50 mg, but you should have blood work to determine dosage)
http://www.lef.org/Vitamins-Supplements/Item01002/Iodoral.html
http://iodine4health.com/disease/cancer/cancer.htm

Magnesium/Potassium Aspertate (either of these)
http://www.aor.ca/html/products.php?id=154
http://www.lef.org/Vitamins-Supplements/Item16060/K-Mag-Aspartate-120-tabs-Potassium-Magnesium-Aspartate-Source-Naturals.html

Melatonin (take at night, buy the 3mg dose first and work up to 39mg, then buy the 10mg dose and take 40mg)
http://www.lef.org/Vitamins-Supplements/Item00330/Melatonin.html
http://www.lef.org/Vitamins-Supplements/Item00331/Melatonin.html
http://www.lef.org/magazine/mag99/jan99-protocols.html

Selenium
http://www.lef.org/Vitamins-Supplements/Item00567/Se-methylselenocysteine-SeMC.html

Silymarin
http://www.lef.org/Vitamins-Supplements/Item00702/Mega-Silymarin-with-Isosilybin-B.html

Sulforaphane
http://www.aor.ca/html/products.php?id=95
http://www.broccosprouts.com/sprouts/story.htm

Zinc
http://www.lef.org/Vitamins-Supplements/Item00915/OptiZinc.html

Zyflamend
http://www.newchapter.com/products/zyflamend

I also take LDN (4.5 mg at night) and DL-phenylalanine (500 mg). See thread here:
https://thedcasite.com/dcaforum/DCForumID10/161.html

And I think I will soon add MMS after the holidays when things settle down at home.
http://miraclemineral.org/

This is what I'm doing for my stage III BC, but I encourage everyone to do their own homework!

Take care,
Sandra


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My Supplements with Links [View All], Sandramoderator, 10:57 PM, Jan-01-09, (0)  
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rtshinn
Member since Mar-7-07
119 posts
Jan-01-09, 11:15 PM (PST)
Click to EMail rtshinn Click to send private message to rtshinn Click to view user profileClick to add this user to your buddy list  
1. "RE: My Supplements with Links"
In response to message #0
 
   Wow! I'll forward this to my wife, but I bet she won't take that much!

Well, you've been on DCA from the beginning (early 2007), and have made many additions and subtractions in your regimen.

How are the results so far?
Have you had any tests done (CT, etc) since, that indicate your progress?
I understand that in Canada you have to be careful or else you could be cut off from 'the system' if you need tests.



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Sandramoderator
Member since Feb-27-07
801 posts
Jan-01-09, 11:29 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
3. "RE: My Supplements with Links"
In response to message #1
 
Hi Robert,
Well, I haven't been taking DCA the whole time - at the beginning, no one knew to cycle on and off the stuff. I took several months off doing other things while my myelin healed and my tremors subsided. I was cut off (CT's etc) shortly after I was diagnosed - when I refused conventional treatment. My most recent blood work showed near normal levels of tumor markers and I have no evidence of mets. The tumor is still there, but I think much of it is dead. I may have lymph involvement now, but it is hard to tell whether that may just be my body trying to clear dead tumor cells. When I refused conventional treatment, my surgeon gave me two years. This month will be three years since my diagnosis. I never like doing what I'm told.

My best to you and your wife,
Sandra


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parachute
Member since Mar-20-07
60 posts
Jan-02-09, 05:14 AM (PST)
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6. "RE: My Supplements with Links"
In response to message #3
 
   "I never like doing what I'm told."

There's nothing like understatement :-)

Happy New Year Sandra :-)

— Parachute


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-02-09, 08:02 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
9. "RE: My Supplements with Links"
In response to message #6
 
Heh, thanks Parachute. Pot/kettle

I must have been writing post #7 while you were posting this.

Happy New Year,
Sandra


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rtshinn
Member since Mar-7-07
119 posts
Jan-01-09, 11:19 PM (PST)
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2. "RE: My Supplements with Links"
In response to message #0
 
   P.S.
Happy New Year!


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davidportia
Member since Jul-23-08
67 posts
Jan-02-09, 01:37 AM (PST)
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4. "RE: My Supplements with Links"
In response to message #0
 
   Hi, Sandra,
Happy New Year to you!
This is the best New Year gift that we receive.

Wish you all the best,
David


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-02-09, 05:25 AM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
7. "RE: My Supplements with Links"
In response to message #4
 
Thanks David and Robert

I really wrestled with whether or not to post a Merry Christmas to all, but I just couldn't bring myself to - in light of the people who've lost loved ones this year. My heart goes out to them... I hope DCA will make a difference for people in the future, to reduce needless suffering and death. Someday, I hope there will be a tribute to all the people who pioneered this drug - especially the ones who are no longer with us.

Love and best wishes,
Sandra


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Vitaminboss
Member since Mar-3-07
87 posts
Jan-02-09, 02:59 AM (PST)
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5. "RE: My Supplements with Links"
In response to message #0
 
   Sandra,

A word of caution on some of your stated supplements (not sure of your health status).

1. Benfotiamine as is Thiamine, a cancer rocket fuel. You might as well have a few spoons of Ribose (super rocket fuel for cancer cells). In Russia, they have a better compound used for cardiac patients which is an ideal substance for non-cancer patients. Its cocarboxylase or Thiamine Pyrophosphate (TPP). Does wonders, but once again NOT for cancer patients!.

2. Vitamin B6 - feeds cancer cells, assists tumors by increasing protein synthesis and DNA synthesis.

4. Folic Acid best food for any embryonic growth, whether a fetus or a cancer. Data shows colon cancer cells explode in proliferative capacity thanks to folate. Hence a few "anti-folate" chemotherapy agents, some of which are used to cure women whos fetus's turn into cancers to stop placental growth and used to be the agent of choice for testicular cancer patients (Methotrexate). Natural folate from juicing leafy vegetables (folate stems from "leaf" in latin) is a good way to prevent cancer since its also in a natural state with oxygenating chlorophyll and other anti-cancer phytonutrients. As synthetic isolates, some B-vitamins can actually cause the few cancer cells that everyone has to proliferate out of control. That’s why prenatal vitamins are loaded with folate, to prevent neural tube defects, in cancer it doesn’t promote differentiation, but stimulates proliferation.

5. Lipoic acid taken in absence of the Kansas University high dose IV C protocol can do harm by enhancing the GLUT-1 receptors on cancer cells increasing their capacity to obtain sugar for growth.

6. 8,000 IUs of Vitamin D daily can be toxic. 2,000 IU’s for 30 days has been shown to increase plasma levels of active vitamin D3 well into the high saturation range. Nature is brilliant, by tanning the skin after a sunburn, it decreases the capacity to further synthesize excess vitamin D. So if one got a megadose of 20,000 IUs after a day in the tropics, the next exposure will not produce nearly as much. Our endogenous lab has more wisdom than synthetic chemicals. Be ware. Although I do agree with taking D3 for cancer patients, not enough to make them sick.

7. As far as vitamin E, I go with a mixed tocopherols formula. Single isolates cause imbalances, after all, in nature they are found together.. But that’s a personal preference.

8. The ImmuneFX product sounds great, for healthy people it would be a nice prophylactic, however cancer patients need stronger immune stimulants. ImmuneFX used the ground up mycelium of medicinal mushrooms, which contain chitin fiber and a low concentration of proteoglycans, and polysaccharides. All research on immune stimulation have been done using hot water or alcohol extracts of mycelia or fruitbodies. I recommend: Biobran (MGN-3) for non lymphatic cancers or cancers with not so large masses (as it can cause increase in size temporarily via migration of lymhocytes), Beta-Glucan by southeastern corp, PSK by mushroom science (Krestin in Japan), or Transfer Factor Plus by 4life instead of Biobran.

9. Melatonin- Hormone, be careful with hormones as in vitro on some cancers it proves beneficial, however all cancers possess difference receptors and no one can tell how each person is wired. Other pineal hormones have shown to be anti-tumorigenic(epithalamine), but im assuming there must be a synergy involved. How it affects your



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Sandramoderator
Member since Feb-27-07
801 posts
Jan-02-09, 06:45 AM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
8. "RE: My Supplements with Links"
In response to message #5
 
Hi Vitaminboss,

This list is a 'package deal' - especially for people taking DCA.
I'll answer you as best I can, point by point below:


>1. Benfotiamine as is Thiamine, a cancer rocket fuel. You
>might as well have a few spoons of Ribose (super rocket fuel
>for cancer cells). In Russia, they have a better compound
>used for cardiac patients which is an ideal substance for
>non-cancer patients. Its cocarboxylase or Thiamine
>Pyrophosphate (TPP). Does wonders, but once again NOT for
>cancer patients!.

Several papers on DCA use show that it lowers thiamine levels in users. Also, for any people following the caffeine & DCA protocol, caffeine lowers thiamine (and vitamin D) levels as well.
Search PubMed for 'DCA thiamine'. Here's just one quote:
'...We conclude that stimulation by DCA of thiamine-requiring enzymes may lead to depletion of total body thiamine stores...'
http://www.ncbi.nlm.nih.gov/pubmed/2318357?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


>2. Vitamin B6 - feeds cancer cells, assists tumors by
>increasing protein synthesis and DNA synthesis.

Toxicology Paper on DCA discusses Oxalic Acid build up. B-6 and magnesium prevent this.
https://thedcasite.com/dcaforum/DCForumID1/235.html

>4. Folic Acid best food for any embryonic growth, whether a
>fetus or a cancer. Data shows colon cancer cells explode in
>proliferative capacity thanks to folate. Hence a few
>"anti-folate" chemotherapy agents, some of which are used to
>cure women whos fetus's turn into cancers to stop placental
>growth and used to be the agent of choice for testicular
>cancer patients (Methotrexate). Natural folate from juicing
>leafy vegetables (folate stems from "leaf" in latin) is a
>good way to prevent cancer since its also in a natural state
>with oxygenating chlorophyll and other anti-cancer
>phytonutrients. As synthetic isolates, some B-vitamins can
>actually cause the few cancer cells that everyone has to
>proliferate out of control. That’s why prenatal vitamins are
>loaded with folate, to prevent neural tube defects, in
>cancer it doesn’t promote differentiation, but stimulates
>proliferation.

I'm not going to say that Folic Acid is essential. Lack of it though can mask a vitamin B-12 deficiency and B-12 is necessary to reduce demyelination. Folate, B-6 and B-12 are all involved in proper nerve/brain function.

>5. Lipoic acid taken in absence of the Kansas University
>high dose IV C protocol can do harm by enhancing the GLUT-1
>receptors on cancer cells increasing their capacity to
>obtain sugar for growth.

https://thedcasite.com/alpha_lipoic_acid_and_dca.html

>6. 8,000 IUs of Vitamin D daily can be toxic. 2,000 IU’s
>for 30 days has been shown to increase plasma levels of
>active vitamin D3 well into the high saturation range.
>Nature is brilliant, by tanning the skin after a sunburn, it
>decreases the capacity to further synthesize excess vitamin
>D. So if one got a megadose of 20,000 IUs after a day in the
>tropics, the next exposure will not produce nearly as much.
>Our endogenous lab has more wisdom than synthetic chemicals.
>Be ware. Although I do agree with taking D3 for cancer
>patients, not enough to make them sick.

I live where there is about 7 hours of daylight in winter - when the sun is even out - and my shadow is always much taller than I am. There are many studies of people taking higher doses than I am for long periods of time.
https://thedcasite.com/dcaforum/DCForumID10/350.html

>7. As far as vitamin E, I go with a mixed tocopherols
>formula. Single isolates cause imbalances, after all, in
>nature they are found together.. But that’s a personal
>preference.

http://jn.nutrition.org/cgi/reprint/134/12/3458S

>8. The ImmuneFX product sounds great, for healthy people it
>would be a nice prophylactic, however cancer patients need
>stronger immune stimulants. ImmuneFX used the ground up
>mycelium of medicinal mushrooms, which contain chitin fiber
>and a low concentration of proteoglycans, and
>polysaccharides. All research on immune stimulation have
>been done using hot water or alcohol extracts of mycelia or
>fruitbodies. I recommend: Biobran (MGN-3) for non lymphatic
>cancers or cancers with not so large masses (as it can cause
>increase in size temporarily via migration of lymhocytes),
>Beta-Glucan by southeastern corp, PSK by mushroom science
>(Krestin in Japan), or Transfer Factor Plus by 4life instead
>of Biobran.

I couldn't find any PubMed studies on MGN-3 use in humans, and I've read that rice beta glucans are not as bioavailable as mushroom derived ones. I agree PSK is good stuff as well. I chose ImmuneFX because it covers a lot of bases in one pill for a reasonable price point.

>9. Melatonin- Hormone, be careful with hormones as in vitro
>on some cancers it proves beneficial, however all cancers
>possess difference receptors and no one can tell how each
>person is wired. Other pineal hormones have shown to be
>anti-tumorigenic(epithalamine), but im assuming there must
>be a synergy involved. How it affects your

Cancer doses average between 3-50 mg per day.

http://www.lef.org/magazine/mag2002/mar2002_report_melatonin_02.html
http://www.lef.org/magazine/mag2007/jun2007_nu_melatonin_01.htm


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Vitaminboss
Member since Mar-3-07
87 posts
Jan-02-09, 08:09 PM (PST)
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10. "RE: My Supplements with Links"
In response to message #8
 
   So basically your taking several different highly proliferative substances to counter the effects of one single anti-proliferative compound... I'm hoping there is a net gain in benefit from this cocktail.

Rice bran does not contain polysaccharides, MGN-3 contains hemicellulose arabonoxylane compounds. These are produced by the fermentative action of enzymes from shiitake mushrooms when they break down the rice bran. It is actually very well documented and the best part is, there is no tolerance build up or loss of hyposensitivity with time as encountered with mushroom based immune stimulants. Also, it is highly stimulative in the most advance immune suppressed patients. It is ideal to use with adjuvant cytotoxics or post surgical debulking.

I've noticed that highly glycolytic cancers that show high FDG uptake values on PET scans respond better to therapies that exploit the warburg effect (high dose ascorbate, poly-mva, perhaps DCA as well). Although of those 3, I'd say DCA has too many side effects to make it worth taking without any supervision. Too bad its not considered a mainstream chemotherapeutic agent, but I've personally learned the hard way that self-medicating with potentially toxic chemicals can be undesirable.


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-02-09, 08:16 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
11. "RE: My Supplements with Links"
In response to message #10
 
Well, this site is about DCA use, so I guess I wouldn't be here if I weren't using it.


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dimitriskmoderator
Member since Mar-19-08
194 posts
Jan-03-09, 00:59 AM (PST)
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13. "RE: My Supplements with Links"
In response to message #10
 
   >So basically your taking several different highly
>proliferative substances to counter the effects of one
>single anti-proliferative compound... I'm hoping there is a
>net gain in benefit from this cocktail.

Peripheral neuropathy is a side effect for most chemos. And they treat these side effects with B1 and the other stuff, like in DCA protocols. I really don't know if and how much proliferative are all these vitamins and what the net gain is finally, and this is what we are trying here to find out. We are not investigating DCA alone, B1 alone, or R+LA alone, but all together as a protocol against cancer. And for many people it works pretty well.

What is your opinion? That this protocol does not work at all, or you have a better protocol to suggest?

> Although of those 3, I'd say
>DCA has too many side effects to make it worth taking
>without any supervision.

Regarding DCA side effects, my sister uses it without interruption since April 2008 (she started at 11mg/Kg 5-2, and now she takes 20mg/Kg 4-3). So far she has noticed no side effects at all.

Her story is here https://thedcasite.com/dimitrisk_report.html
The last update is that she had a surgery a week ago and she removed the tumor. It went pretty well and surgeon said that the picture was much better than he was expecting (not spread). We are expecting the biopsy to know if the edges were clear. It will come out in a few weeks and I would give more information about it. She will keep on with the same protocol at least for 2-3 more months (DCA, LDN and supplements).


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Vitaminboss
Member since Mar-3-07
87 posts
Jan-04-09, 11:32 PM (PST)
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14. "RE: My Supplements with Links"
In response to message #13
 
   dimitrisk,

In some individuals DCA may, in addition with ALA cause severe hypoglycemia. Would it be worth potentially going into a diabetic coma by flirting with the possibility of managing a tumor? Keep in mind that negatively affecting quality of life, in turn negatively affects patient outcome. For high grade cancers I'm a proponent of high dose ascorbate IV, injectable artemisinin/artesunate or poly-mva in addition to a strong immune enhancer and potent pancreatic enzymes. Theres really a 4 punch protocol if you look at alternative cancer therapy:

Cytotoxics - Direct cancer cell killers - IVC, LaPd (poly-mva), ART compounds, Cantron, Entelev.

Immune Enhancers - Activators of cellular and humor immunity - Biobran MGN3**, Transfer Factor Plus, Potent 1-3d, 1-6d Beta-Glucan, PSK.

Pancreatic Enzyme based formulas - Disrupt malignant processes, remove debris, expose tumor cells to immune cells, improve circulation, catalyze inflammatory reactions, and sometimes even shrink tumors size.

Antiangiogenics - Frozen Shark cartilage (Comitris), C-statin (bindweed), ART compounds and others.

Also important to throw in are bioenergetic catalysts such as NADH CoE1, and Ubiquinol CoQH2.

As far as deficiencies go, a good FOOD BASED multi-nutrient is far more effective than megadoses of isolated vitamins and minerals in an imbalanced proportion that causes drastic deficiencies in other nutrients. I prefer Megafood brand multivitamin and minerals in Foodstate form. The one a day (isnt really a one a day) iron free as a personal favorite.

Surgical debulking where and when possible makes therapy MUCH easier. Also, patients who chose not to surgically resect primary tumors show much better therapeutic response and tumor aggression in those where primary tumor was excised. Unless of course the primary cancer is huge and there is a good post debulking therapy planned.

** Donot take MGN3 if you have significant lymph node metastases. It significantly increases lymphocyte production and infiltration that can triple tumor size and can cause PAIN..


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-05-09, 03:12 AM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
15. "RE: My Supplements with Links"
In response to message #14
 
Vitaminboss,

Regarding the possible risk of hypoglycemia with DCA - that is relatively low with dosages between 10-15 mg/kg/day as advocated by this site. (People who are diabetic learn to live with this possibility every day of their lives.) It is easy to be responsible, eat smaller more frequent meals, and carry a snack. This is a small price to pay to cure or prevent the progression of cancer.

I'd suggest you start a new thread with your protocol rather than discussing it further here. It would also be helpful if you'd cite some peer reviewed articles.

Thanks,
Sandra


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dimitriskmoderator
Member since Mar-19-08
194 posts
Jan-05-09, 10:02 PM (PST)
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17. "RE: My Supplements with Links"
In response to message #14
 
   Thanks a lot for your detailed answer. It is really important to start a new thread what your protocol.

>In some individuals DCA may, in addition with ALA cause
>severe hypoglycemia.

My sister takes DCA + 3x120 R+ALA for 10 months now without any problem. Every medicine (even aspirin) can be very dangerous for certain people, but can treat many others. This is no reason to withdraw it. As soon as a patient faces serious side effects has to stop his treatment immediately.


>I prefer Megafood brand
>multivitamin and minerals in Foodstate form. The one a day
>(isnt really a one a day) iron free as a personal favorite.

What do you think about this one?
http://www.iherb.com/ProductDetails.aspx?pid=3988&at=0


>
>Surgical debulking where and when possible makes therapy
>MUCH easier. Also, patients who chose not to surgically
>resect primary tumors show much better therapeutic response
>and tumor aggression in those where primary tumor was
>excised. Unless of course the primary cancer is huge and
>there is a good post debulking therapy planned.

Excuse my english, but I can't understand what you mean here. Is surgery a good idea or not?


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Vitaminboss
Member since Mar-3-07
87 posts
Jan-06-09, 05:02 AM (PST)
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18. "RE: My Supplements with Links"
In response to message #17
 
   >Thanks a lot for your detailed answer. It is really
>important to start a new thread what your protocol.
>
>>In some individuals DCA may, in addition with ALA cause
>>severe hypoglycemia.
>
>My sister takes DCA + 3x120 R+ALA for 10 months now without
>any problem. Every medicine (even aspirin) can be very
>dangerous for certain people, but can treat many others.
>This is no reason to withdraw it. As soon as a patient faces
>serious side effects has to stop his treatment immediately.
>
>
>>I prefer Megafood brand
>>multivitamin and minerals in Foodstate form. The one a day
>>(isnt really a one a day) iron free as a personal favorite.
>
>What do you think about this one?
>http://www.iherb.com/ProductDetails.aspx?pid=3988&at=0
>
>
>>
>>Surgical debulking where and when possible makes therapy
>>MUCH easier. Also, patients who chose not to surgically
>>resect primary tumors show much better therapeutic response
>>and tumor aggression in those where primary tumor was
>>excised. Unless of course the primary cancer is huge and
>>there is a good post debulking therapy planned.
>
>Excuse my english, but I can't understand what you mean
>here. Is surgery a good idea or not?

All megafood supplements that are foodstate are great.

As far as surgery, i meant to say, if a primary cancer has not spread, it is dealt with easier with alternative treatments if it is not surgically removed because they become more aggressive when ressected, however metastases when significant are better to have surgically removed when possible. Micro-metastatic cells can be eradicated more easily than tumors.


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-02-09, 08:32 PM (PST)
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12. "RE: My Supplements with Links"
In response to message #8
 
Just an addition - I found a study showing folic acid improved efficacy of the chemo drug 5-FU

http://www.lef.org/protocols/cancer/alternative_cancer_therapies_01.htm

'The effectiveness of 5-fluorouracil (5-FU), a chemotherapy agent used to treat breast cancer, was improved when it was administered in combination with folic acid (Kreienberg R 1998). 5-FU is also commonly used in colon, liver, and pancreatic cancers, but has not shown a high degree of efficacy (Christopoulou A 2004). A randomized trial of patients with metastatic colorectal carcinoma compared the effects of 5-FU administered alone and in combination with folic acid. Compared to the group receiving 5-FU alone, the patients receiving 5-FU plus folic acid experienced a 76 percent overall tumor reduction. Survival in the group receiving 5-FU plus folic acid was 47 percent greater than in the group receiving 5-FU alone. The addition of folic acid to this chemotherapy drug regimen resulted in an improved therapeutic profile and significantly prolonged survival time (Loffler TM et al 1992).'


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-05-09, 08:59 PM (PST)
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16. "RE: My Supplements with Links"
In response to message #0
 
One correction to the links for my supplements. LEF has made a NEW curcumin. I've been using it, but forgot to update the link. Only 1 pill per day is needed:

http://www.lef.org/Vitamins-Supplements/Item00407/Super-Bio-Curcumin.html

And - I thought this link about treating or minimizing neuropathy was really good:

http://www.lef.org/protocols/neurological/neuropathy_01.htm


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Vitaminboss
Member since Mar-3-07
87 posts
Jan-06-09, 05:05 AM (PST)
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19. "RE: My Supplements with Links"
In response to message #16
 
   >One correction to the links for my supplements. LEF has
>made a NEW curcumin. I've been using it, but forgot to
>update the link. Only 1 pill per day is needed:
>
>http://www.lef.org/Vitamins-Supplements/Item00407/Super-Bio-Curcumin.html
>
>And - I thought this link about treating or minimizing
>neuropathy was really good:
>
>http://www.lef.org/protocols/neurological/neuropathy_01.htm


Sandra,

according to studies, the most biologically active and potent curcumin is the one formulated with Bioperine. Has shown overall higher bioavailability. I take the Dr.'s Best one personally.


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-06-09, 05:14 AM (PST)
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21. "RE: My Supplements with Links"
In response to message #19
 
http://www.lef.org/magazine/mag2007/oct2007_report_curcumin_01.htm

Explanation of the newer curcumin


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satx
Member since May-9-07
103 posts
Jan-06-09, 05:13 AM (PST)
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20. "RE: My Supplements with Links"
In response to message #16
 
   http://www.iherb.com/ProductDetails.aspx?pid=6700&at=0


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satx
Member since May-9-07
103 posts
Jan-06-09, 05:17 AM (PST)
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22. "RE: My Supplements with Links"
In response to message #20
 
   Sorry, wrong one

http://www.iherb.com/ProductDetails.aspx?pid=1991456822181762381&at=0


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Dave
Member since Mar-5-07
41 posts
Jan-21-09, 01:27 AM (PST)
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23. "RE: My Supplements with Links"
In response to message #0
 
   Hi Sandra

I've noticed that you are now using super curcumin with bioprene as opposed to super bio-curcumin (both from LEF). I have been using curcumin as well for a couple of years and was trying to determine if I should switch to one of these two options. I understand the difference between the two and was just wondering about your thoughts regarding the benefits of one over the other.

Thanks
Dave


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-21-09, 02:33 AM (PST)
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24. "RE: My Supplements with Links"
In response to message #23
 
Hi Dave - I made a correction to my list in post # 16. I'm using the new stuff.


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PTB
Member since May-19-08
9 posts
Jan-21-09, 08:47 PM (PST)
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25. "RE: My Supplements with Links"
In response to message #24
 
   Ever consider liposomal ????
http://www.letstalkhealth.com/store/index.php?main_page=index&cPath=24


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Sandramoderator
Member since Feb-27-07
801 posts
Jan-21-09, 09:24 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
26. "RE: My Supplements with Links"
In response to message #25
 
Yeah, after reading the discussion on this thread, I'm going to add back CoQ-10 to my list. Seems it works with acetyl-L-carnitine, which I'm also taking.

https://thedcasite.com/dcaforum/DCForumID4/79.html

Thanks,
Sandra


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crono5
Member since Aug-2-07
75 posts
Feb-02-09, 11:52 AM (PST)
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27. "RE: My Supplements with Links"
In response to message #26
 
Some info on Biocurcumax/BCM-95:

http://margaret.healthblogs.org/2008/03/18/it-didnt-work/

check out this blog lot of interesting things there

http://apoptoza.pl
http://nadzieja-glejak.pun.pl
http://glejak.pl/forum


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Dave
Member since Mar-5-07
41 posts
Feb-02-09, 04:39 PM (PST)
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28. "RE: My Supplements with Links"
In response to message #27
 
   This is the second reference that I have come across where the efficacy of the new curcumin was questioned. I have been considering switching from the traitional curcumin (3.5 grams / day) to the "new" more bioavailble curcumin but I am now reconsidering. Does anybody have any thoughts on this - thanks.


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Sandramoderator
Member since Feb-27-07
801 posts
Feb-02-09, 09:09 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
29. "RE: My Supplements with Links"
In response to message #28
 
Here are links to both companies who manufacture these versions of curcumin.

http://www.dolcas-biotech.com/
(See the research on the left side of page)

http://www.bioperine.com/reviewed_articles.htm


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Sandramoderator
Member since Feb-27-07
801 posts
Feb-02-09, 10:19 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
30. "RE: My Supplements with Links"
In response to message #28
 
>This is the second reference that I have come across where
>the efficacy of the new curcumin was questioned. I have
>been considering switching from the traitional curcumin (3.5
>grams / day) to the "new" more bioavailble curcumin but I am
>now reconsidering. Does anybody have any thoughts on this -
>thanks.

Hi Dave,

When you consider that LEF sells both versions of this curcumin (the bioperine and the BCM-95) yet THEY did a study with human volunteers and found that the BCM-95 is more bioavailable, I'm convinced that they have done their homework and I'm going to stick with the newer BCM-95 curcumin.

Take care,
Sandra


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Sandramoderator
Member since Feb-27-07
801 posts
Jun-07-09, 03:52 PM (PST)
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31. "RE: My Supplements with Links"
In response to message #0
 
I just read some information about various forms of B-12. Apparently, methyl B-12 (Methylcobalamin) is supposed to be better so I'm switching to that.

http://www.iherb.com/Jarrow-Formulas-Methyl-B-12-1000-mcg-100-Lozenges/129?at=0
http://www.whfoods.com/genpage.php?tname=nutrient&dbid=107



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michele lee
Member since May-26-09
69 posts
Jun-21-09, 04:56 PM (PST)
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32. "RE: My Supplements with Links"
In response to message #31
 
   I would like to add to the remarks on supplementsa: First why would you want to enhance your mitochondrial energy (ATP)? Studies show that depleting ATP makes cancer cells vulnerable and causes apoptosis outright. This is the strategy behind the use of paw paw
http://www.pawpawresearch.com/

Also many people here talk about B-vitamans. I'd like to point out that B 6,9,12 are methyl donors. and many if not all cancers are hypermethylated. For a cancer that is hyper or abberantly methylated, methyl donors fuel cancer. Some chemotherapies cause abberant methylation that is responsible for drug resistance. Human trials are ongoing using dicitaben, a methyltransferase inhibitor to reverse this. (methyltransferase or Mtase is the enzyme responsible for methylation.) This is also why selenium is a good supplement to take - it is an Mtase inhibitor. There are studies to test which inhibitors are most effective and decitiben and a synthetic selenium called p-xsc which can be purchase over the internet are most effective.

Silymiran was mentioned by someone with breast cancer. If that cancer is ER-positive I would caution the person taking it to stop as milk thistle is quite estrogenic.

Regards,
Michele


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Sandramoderator
Member since Feb-27-07
801 posts
Jun-21-09, 09:04 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
33. "RE: My Supplements with Links"
In response to message #32
 
>I would like to add to the remarks on supplementsa: First
>why would you want to enhance your mitochondrial energy
>(ATP)? Studies show that depleting ATP makes cancer cells
>vulnerable and causes apoptosis outright. This is the
>strategy behind the use of paw paw
>http://www.pawpawresearch.com/

I wanted to enhance mito function because that is one of the things DCA does. I think DCA may conflict with Paw Paw in its mechanism of action - Paw Paw seems to shut down ATP production, and DCA should in theory enhance it. Would need to have some trial results to know for certain.

>Also many people here talk about B-vitamans. I'd like to
>point out that B 6,9,12 are methyl donors. and many if not
>all cancers are hypermethylated. For a cancer that is hyper
>or abberantly methylated, methyl donors fuel cancer. Some
>chemotherapies cause abberant methylation that is
>responsible for drug resistance. Human trials are ongoing
>using dicitaben, a methyltransferase inhibitor to reverse
>this. (methyltransferase or Mtase is the enzyme responsible
>for methylation.) This is also why selenium is a good
>supplement to take - it is an Mtase inhibitor. There are
>studies to test which inhibitors are most effective and
>decitiben and a synthetic selenium called p-xsc which can be
>purchase over the internet are most effective.

The reason for B vitamins with DCA is because use of it depletes them and causes side effects like PN. See this thread:
https://thedcasite.com/dcaforum/DCForumID4/80.html
and other papers on DCA and thiamine.

>Silymiran was mentioned by someone with breast cancer. If
>that cancer is ER-positive I would caution the person taking
>it to stop as milk thistle is quite estrogenic.

Maybe the jury is still out on that one, because I found this study showing silibinin (which is what I was taking) is useful against ER+ breast cancer.
http://mct.aacrjournals.org/content/8/6/1606.abstract


Best of luck to you,
Sandra


>Regards,
>Michele


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michele lee
Member since May-26-09
69 posts
Aug-14-09, 08:46 AM (PST)
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34. "RE: My Supplements with Links"
In response to message #33
 
   Hey Sandra,
I was looking at your list again, and I agree with VB on his points, but especially on vitamin D. Vitamin D is an important supplement for cancer but it has a U-shaped dose response, which means that a vitamin D deficiency can cause cancer, but taking too much can also cause cancer. The current tolerable upper limit of intake (UL) of vitamin D for adults, set by the Food and Nutrition Board of the Institute of Medicine, is 2,000 IU/day. You are taking dangerous amounts of vitamin D. You can get up to 20,000 IU of vitamin D from 10 minutes in the sun BTW, and you can’t get too much vitamin D from the sun. Or maybe a sun lamp?

I don’t take vitamin E supplements because research is has returned mixed results with it. If you do take it you should take a “mixed tocopheryl” product not “d-alpha tocopheryl.” D-alpha supplementation reduces the amount of gamma tocopheryl, which is also important in inhibiting cancer.

I3C also carries some risk:
It is marketed and sold as an anti-estrogen and a cancer inhibitor. Research has given I3C/DIM some solid credentials for these claims; however, studies continue to produce contradictory results.

I3C is produced during the breakdown of glucobrassicin, found in cruciferous vegetables. When I3C reaches the acidic environment of the stomach, its molecules combine to form Diindolylmethane (DIM).
I3C and DIM are thought to fight cancer by inhibiting estrogen and promoting cell cycle arrest and apoptosis. Most studies attribute all of these activities to the induction of phase II detoxification enzymes via binding and activation of the aryl hydrocarbon receptor 17.

But the attachment of DIM to the aryl hydrocarbon receptor (AhR) can cause as well as inhibit cancer. DIM attaches to AhR in the cytoplasm. It travels to the nucleus of the cell and binds to DNA, activating phase I and II enzymes. And while both phases are part of the detoxification of carcinogens, including estrogens, Phase I enzymes are viewed as undesirable, because they pose a risk of activating carcinogens that depend on such enzymes. It is the job of phase II enzymes to carry off activated carcinogens before they can do damage. So Phase I enzymes are associated with risk, whereas phase II enzymes are considered cancer-inhibiting. Induction of Phase I enzymes is thought to have some responsibility for DIM’s cancer promoting activities 18.

Still, a number of studies conclude that DIM overcomes its estrogenic and cancer promoting activities with the induction of powerful anticancer activities. Several studies indicating that I3C inhibits estrogen found that it changes estrogen’s course away from the 16 alpha-hydroxylation pathway or from a tumor promoter to tumor suppressor pathway.

estradiol can be metabolized into either 16 alpha-hydroxylation (16OHE1), a highly estrogenic tumor promoter or 2-hydroxyestrone (2OHEI), a tumor suppressor and antiestrogen. Studies have found that I3C and DIM supplementation “consistently increased urinary 2OHE1 levels in pre and post-menopausal women 1, 2, 3.” This indicates that DIM is effective in guiding estrogen toward an anti-cancer pathway. And this theory is supported by attempts to establish an association between 20HE1:16OHE1 ratios in urinary levels and cancer risk, which found women with breast cancer had lower ratios of 2OHE1:16OHE1 4, 5, 6. Other studies, however, have found I3C actually enhances the transcription of estrogen-responsive genes, supporting the notion that I3C activates estrogen receptors independent of ligands 7, 8, 9.

In a study on rats fed 5 mg/kg of DIM every other day, MCF-7 (estrogen sensitive) breast cancer cells were inhibited. Researchers concluded that “DIM represents a new class of relatively non-toxic AhR-based anti-estrogens that inhibit E2-dependent tumor growth in rodents and current studies are focused on development of analogs for clinical treatment of breast cancer 14.”
A study found Indole-3 inhibited ERalpha, suppressing estrogen-responsive genes, pS2, cathepsin-D and upregulating BRCA115. (BRCA1 is a tumor suppressor gene involved in DNA repair.)

Researchers found that DIM “exhibits potent antiproliferative and antiandrogenic properties in androgen-dependent human prostate cancer cells 16.”

A study by the University of California attempted to rectify the contradictions in I3C research with a cell culture study. DIM acted as a ligand-independent ER activator through a combination of PKA ad MAPK signaling. (Estrogen receptors were activated via cell signaling, without the presence of actual estradiol or other ligands.) But researchers concluded that the estrogenic activity is overcome by the activation of antiproliferation activities that counter the estrogenic effects. Researchers went on to suggest that while estrogenic effects are overcome with regard to cancer, they may be beneficial to other tissues, such as bones and brain.
Despite the apparent estrogenic effects, DIM paradoxically exerts potent cytostatic effects in vitro and in vivo 16, 17, 18. DIM shows estrogenic and antiproliferative activities at the same concentrations in Ishikawa cells 17. Thus, we propose that DIM simultaneously activates an antiproliferative pathway that counters the estrogenic effects. Both estrogenic and antiproliferative effects may be elicited through similar signaling pathways… Overall, however, DIM is effective at controlling the growth of estrogen-dependent cancer cells. Given the association of endometrial cancer in women using tamoxifen for the control of breast cancer, the potent cytostatic effects of DIM in both breast and uterine tissues may prove significant. In light of such advantage over tamoxifen, the mechanism by which DIM exerts simultaneous estrogenic effects is important to determine given that DIM may also exert similar estrogenic effects in other tissues such as the brain, bone, and cardiovasculature. Such effects are beneficial and sought after in the search for improved selective ER modulators for the treatment of breast cancer. Whether DIM may exert estrogenic effects in these tissues by the same mechanism we have discovered in uterine cancer cells remains to be determined. Characterization of these effects will be informative because DIM already shows promise as a therapeutic agent for cancers of the female reproductive tract.
Mol Endocrinol. 2004;18(2):291-302

16. Riby JE, Chang GH, Firestone GL, Bjeldanes LF 2000 Ligand– independent activation of estrogen receptor function by 3, 3'– diindolylmethane in human breast cancer cells. Biochem Pharmacol 60:167–177
17 Leong H, Firestone GL, Bjeldanes LF 2001 Cytostatic effects of 3, 3'– diindolylmethane in human endometrial cancer cells result from an estrogen receptor– mediated increase in transforming growth factor– expression. Carcinogenesis 22:1809–1817
18. Chen I, McDougal A, Wang F, Safe S 1998 Aryl hydrocarbon receptor– mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis 19:1631–1639

But the researchers at the University of California came up short in explaining why so many studies have found I3C to cause cancer in animals. According to the Linus Pauling Institute, “I3C has been found to inhibit the development of cancer in animals when given before or at the same time as a carcinogen. However, in some cases, I3C enhanced the development of cancer in animals when administered after a carcinogen.” In fact, a number of rodent studies found that I3C promoted cancers of the liver, thyroid, uterus and colon. 7, 8, 9, 10, 11, 12 A study on fish also found that DIM promoted “liver cancer in trout by estrogenic pathways 13.”

It appears that certain cell signaling activities influencing the behavior of DIM have yet to be understood. Using I3C or DIM supplements carries a risk – especially of fueling an existing cancer. Fortunately a diet rich in cruciferous vegetables does not carry such risk.
1. McAlindon TE, Gulin J, Chen T, Klug T, Lahita R, Nuite M. Indole-3-carbinol in women with SLE: effect on estrogen metabolism and disease activity. Lupus. 2001;10(11)79-783. (PubMed)
2. Michnovicz JJ, Adlercreutz H, Bradlow HL. Changes in levels of urinary estrogen metabolites after oral indole- 3- carbinol treatment in humans. J Natl Cancer Inst. 1997;89(10)18-723. (PubMed)
3. Dalessandri KM, Firestone GL, Fitch MD, Bradlow HL, Bjeldanes LF. Pilot study: effect of 3,3'- diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. Nutr Cancer. 2004;50(2):161-167. (PubMed)
4. Ho GH, Luo XW, Ji CY, Foo SC, Ng EH. Urinary 2/16 alpha– hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein- 3 and a potential biomarker of breast cancer risk. Ann Acad Med Singapore. 1998;27(2):294-299. (PubMed)
5. Kabat GC, Chang CJ, Sparano JA, et al. Urinary estrogen metabolites and breast cancer: a case-control study. Cancer Epidemiol Biomarkers Prev. 1997;6(7):505-509. (PubMed)
6. Schneider J, Kinne D, Fracchia A, et al. Abnormal oxidative metabolism of estradiol in women with breast cancer. Proc Natl Acad Sci U S A. 1982;79(9):3047-3051. (PubMed)
7. Stoner G, Casto B, Ralston S, Roebuck B, Pereira C, Bailey G. Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole- 3-carbinol. Carcinogenesis. 2002;23(2):265-272. (PubMed)
8. Kim DJ, Lee KK, Han BS, Ahn B, Bae JH, Jang JJ. Biphasic modifying effect of indole- 3- carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form– positive liver cell foci in Sprague-Dawley rats. Jpn J Cancer Res. 1994;85(6):578-583. (PubMed)
9. Kim DJ, Han BS, Ahn B, et al. Enhancement by indole– 3– carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis model. Carcinogenesis. 1997;18(2):377-381. (PubMed)
10. Pence BC, Buddingh F, Yang SP. Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol. J Natl Cancer Inst. 1986;77(1):269-276. (PubMed)
11. Suzui M, Inamine M, Kaneshiro T, et al. Indole- 3- carbinol inhibits the growth of human colon carcinoma cells but enhances the tumor multiplicity and volume of azoxymethane-induced rat colon carcinogenesis. Int J Oncol. 2005;27(5):1391-1399. (PubMed)
12. Yoshida M, Katashima S, Ando J, et al. Dietary indole- 3-carbinol promotes endometrial adenocarcinoma development in rats initiated with N-ethyl-N'- nitro- N- nitrosoguanidine, with induction of cytochrome P450s in the liver and consequent modulation of estrogen metabolism. Carcinogenesis. 2004;25(11):2257-2264. (PubMed)
13. Toxicol Appl Pharmacol. 2001;170(3):191-200
14. Carcinogenesis. 1998 Sep;19(9):1631-9
15. J Nutr . 2000 Dec;130(12):2927-31
16. J Biol Chem . 2003 Jun 6;278(23):21136-45. Epub 2003 Mar 27.
17. Drug Metabol Drug Interact. 2000;17(1-4):159-188
18. Proc Natl Acad Sci U S A. 1991;88(21)543-9547

I think research on silymarin is lacking, but I look at all the studies I can find and then try to make a decision. Here is what I have found:

The primary active ingredient in milk thistle is silymarin, an extract of milk thistle seeds. It is an antioxidant that contains four compounds: silybin (the most active), isosilybin, silychristin, and silydianin. Research has focused on silymarin and its major compound silybin, rather than the plant as a whole. Silymarin is a mixture of flavonolignans, a family of plant-based substances with antioxidant effects. Research has found various antitumorigenic agents in milk thistle, but there is also strong evidence that milk thistle is estrogenic and should be avoided in regard to estrogen sensitive cancers.

According to the National Cancer Institute, studies have shown that milk thistle acts as an antioxidant by strengthening cell walls, stimulating enzymes that break down toxins and by blocking free radicals. Silybin is an antioxidant. It is also known to increase sensitivity to Cisplatin and doxorubicin while reducing their side effects. It aids in arresting the growth of cancer, promoting differentiation and suppressing NF-kB.

The European Journal of Cancer reported that Silybin is valuable in chemo- resistant breast and ovarian cancer lines. It appears to bind with Type II estrogen binding sites, an action that turns off the proliferative effects of the cell (Scambia et al. 1996). In addition, silymarin inhibited the secretion of VEGF, an angiogenic factor. (Jiang et al. 2000).

The University of California (Berkeley) announced that silymarin potently suppressed NF-kB, but TNF-alpha-induced NF-kB was not affected, demonstrating a pathway-dependent inhibition by silymarin. It appears the inhibitory effect of silymarin on NF-kB activation is associated with its liver-protecting properties. Suppression of NF-kB, a key regulator in inflammatory and immune reactions, significantly advances the anticarcinogenic status of silymarin (Saliou et al. 1998).

Studies indicate that milk thistle is effective in treating virtually every type of liver disease, including cirrhosis and alcohol or chemical-induced liver damage. It is such a potent protector against toxins that individuals poisoned by the Amanita mushroom survived the experience when silybin was utilized (Carducci et al. 1996). A healthy liver is essential to detoxification, a process key to restoring health to cancer patients.

A study of milk thistle on prostate cancer found antiproliferative effects. “The four major flavonolignans, when given at concentrations high enough, were all capable of arresting the growth of androgen-dependent and androgen-independent prostate carcinoma cells in vitro 56.”

An experiment by several institutions in the Czech Republic to determine milk thistle’s estrogenicity determined, “several of its compounds behaved as either partial or full ER agonists 57.”

According to Drug Digest, “certain types of breast cancer tumors actually increased in number and/or seriousness when milk thistle was given to female animals with existing breast tumors. Women who have cancers of the breast, ovaries, or uterus or who have other hormone-dependent conditions such as endometriosis or uterine fibroids should not take or use milk thistle plant extract due to its possible estrogenic effects.”


M



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michele lee
Member since May-26-09
69 posts
Aug-14-09, 08:46 AM (PST)
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35. "RE: My Supplements with Links"
In response to message #33
 
   Maybe I should put milk thistle back on my list. Results are not clear.

Here is my list of supplements:

Antioxidants
Vitamin C (Ascorbic Acid) (5 - 10 grams daily) (May be contra-indicated 5 – 7 days after chemotherapy.)

Selenium (methylselenocysteine) (600 mcg to 1 mg 3x daily) Vitamin Research Products
Lycopene (10-15 mg 2x daily)
Co-Enzyme Q10 (400-600 mg daily)
Green Tea Extract (ECGC) (6 grams or more daily). Relentless Improvements offers a high-potency product.

Cancer-fighting Supplements
Cranberry Extract (4 capsules or more 2x daily)
CLA (Conjugated Linolenic Acid) (1 softgel 3x daily)
Fish Oil (3 softgels daily)
Calcium D-Glucarate (1000 mg 3x daily)
Cal Mag Inositol Hexaphosphate & Inositol (IP6 Gold or Enzymatic brands) (6 - 8 capsules 2x daily)

Beta-glucan (3 grams on empty stomach) (www.beta-glucan.com offers a high potency product.)
Spirulina (5 tablets 2x daily)
Niacin (250 mg 3x daily)(It can be taken safely up to 3 grams daily)
Garlic (3 capsules 2x daily)
Lactoferrin “apolactoferrin” (as directed)
Enzymes (digestive or proteolytic) (4-5 tablets on empty stomach 4x daily)
Recommended brands: Jon Barron’s pHi-Zymes, ENZYMEDICA Repair, Vitamin Shoppe Digestive Enzymes (least expensive).

Probiotics as directed

Butyrate (Recommended: Butyrex by T.E. Neesby. Available from Holley Pharmaceuticals.) As
directed.

Multi-Mineral Complex (Recommended: Country Life Total Mins, pHion mineral powder)
Trace Minerals (pHion pH Booster water treatment, Vitamin Shoppe Trace Minerals, etc.)
Inulin powder (Now brand, Vitamin Shoppe Miracle Fiber) (1 tbsp mixed with/taken with minerals
2x daily)

Aspirin (1 twice daily)
* Bone-Up by Jarrow (3 capsules twice daily)
Bone-Up is for bone health, although all contents are good anti-cancer nutrients. It supplies calcium via microcrystaline hydroxyapaitite, which is the most well-absorbed form of calcium and is considered a comprehensive bone nourishment. Bone-Up also provides vitamins K and vitamin D, which are both important cancer-fighting supplements.
* This product is fabulous for bone health as well as cancer prevention; however, I recently noticed that it contains soy, so it isn’t indicated for estrogen-sensitive cancers. Bone Builder, made by Ethical Nutrients is a comparable alternative. It is missing vitamin K, which should be purchased separately. Make sure your vitamin K supplement includes both K1 and K2. I use Life Extension brand. K3 has been found to have many cytotoxic properties as well, but does not seem to be available as a supplement. However, it is available from pharmaceutical suppliers over the Internet.

Regards,
Michele


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Vitaminboss
Member since Mar-3-07
87 posts
Aug-14-09, 10:54 AM (PST)
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36. "RE: My Supplements with Links"
In response to message #35
 
   There will ALWAYS be mixed results, due to the variation of every persons individual biochemistry. Thats why Im against taking any synthetic substances and stick to super-foods and only food grade vitamins and minerals. My brand of choice is megafood. USP grade is chemical isolates and possess no natural wisdom. Foodgrade are fermented with microorganisms and result in naturally chaperoned vitamins in a highly bioavailable food matrix. Retention and utilization is better and it is gentler on the body.

Superfoods are more beneficial because they balance out cellular metabolism and possess many anticancer compounds. Most people dont realize that its NOT ABOUT DOSAGE!! In superfoods and foodgrade supplements, actual amounts can be tiny HOWEVER the effect is more active due to SYNERGY of components in a unique natural balance that our cell recognize and utilize bringing them back to balance at a molecular and submolecular level. If only more people understood what they do to their bodies when they pump in dozens of chemical supplements hoping to achieve a text book effect.. They throw it off balance gambling with ultimate results.

If i were you, I would investigate Bio Algae, Micro Algae, Marine Phytoplankton. VERY powerful substances with anticancer effects. They are COMPLETE cellular nutrition with over 5,000 components. One product is called BAC (www.bionutrition.ca) or www.bioage.com

I also use Ocean's Alive Marine Phytoplankton. It has an amazing detoxifying effect and enhances immunity and energy.

When cellular and physiological homeostasis is achieved and metabolism corrected the body begins to correct itself. At that point i would suggest using a single powerful anti-tumor approach be used that is virtually universal in effect to shrink large tumors. In my opinion thats oxidative therapy with High dose IV vitamin C, unless of course your cells possess catalase (50% chance) in which case it may not work well.

Otherwise trying to take large doses of beneficial micronutrients that showed mixed results in petri dishes and mice is FUTILE!! These nutrients are found linked with other substances in nature that synergize their effect. Once a huge tumor has formed you need a holistic approach to bring back normalcy to the body and then go in and shrink or destroy the tumor. That in itself will help the body heal. Tumors are HUGE burdens on the endocrine system. They deplete the body of the adrenal hormone DHEA creating fatigue and muscle loss not to mention immune suppression. Once tumor burden is lowered the body has more capacity to bring itself back in balance (with the help of superfoods).


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Sandramoderator
Member since Feb-27-07
801 posts
Aug-14-09, 11:05 AM (PST)
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37. "RE: My Supplements with Links"
In response to message #35
 
LAST EDITED ON Aug-14-09 AT 11:13 AM (PST)
 
This list is based on my research and use of DCA. It is NOT for people who are not taking DCA (like Vitaminboss and Michele). I've been saying this for 2 years now. Please see these threads on why B vitamins are needed with DCA:

https://thedcasite.com/dcaforum/DCForumID4/99.html
https://thedcasite.com/dcaforum/DCForumID4/80.html

Also, Medicor is getting great results:

http://www.medicorcancer.com/dca-reports.html

Besides, it's a moot point now because I'm taking artemisinin and have changed my protocol. DCA stopped working for me - I had lymph involvement this winter, which has since reversed with artemisinin.

I think it would be good if you started a new thread on your supplements Michele, thanks.

Best,
Sandra

Oops, forgot to include the artemisinin link:
http://artemisinin.pbworks.com/FrontPage


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