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Conferences DCA Research Topic #109
Reading Topic #109
robmx
Member since May-25-09
59 posts
Nov-24-10, 03:12 PM (PST)
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"Not so good news"
 
   Talked to researcher Brenda Coomber today. Her work shows that DCA does not work with colon cancer. Well it did kill some colon cancer cells in normal culture. It did not work for some cell lines and actually caused some tumors to grow more that control tumors.

http://www.canadaviews.ca/2010/11/22/researcher-finds-anti-cancer-agent-is-no-wonder-drug/

Maybe I am an anomaly but I still think DCA worked/works for me and my colon cancer. Professor Coomber is interested in low oxygen tumor environments and that is where DCA actually can cause tumor growth.

Think I read that somewhere in the past. It is part of my mental picture of DCA. Maybe I read it here. No I read it here (did a search) and it is the same Professor Coomber in an abstract at PubMed back in May 2010. She told me it had been publish a few months ago but this is in May, quite a while ago. Anyway this is where I got the mental picture. Don't actually have to remember things anymore, Google is your memory bank and just in time for me.

And the abstract suggest a greater role for DCA in cell lines SW480 and Caco-2. Wish I knew what cell lines I have.

Maybe my tumors being in the lung and Hylar region are well oxygenated and I have the right cell lines.

Any comments?


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joeyooser
Member since Feb-5-10
14 posts
Nov-24-10, 10:54 PM (PST)
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1. "RE: Not so good news"
In response to message #0
 
   I remember when this was posted before and I believe Sandra had an interesting comment like this - in a low-oxygen environment, that also means very little DCA would be getting to the tumor as well, so it's probably not a factor.

I just had a meeting with an oncologist this morning that said 5FU (the standard base drug for CRC cancer treatment) can actually make things worse in some cases too.


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