See: http://www.fda.gov/cder/regulatory/applications/ind_page_1.htm
... for the official word on this topic.

A verified source of pharma-grade sodium DCA (TCI America) quoted IND rules & regs (law?) as the reason why they could not ship the drug.

But this seems contradictory to me. The entire IND process seems aimed at new drugs ... but DCA is NOT A NEW DRUG ... It has been in use for 25 to 30 years, according to many sources.

Can anybody explain this?

1) a regular pharmacist will not likely be able to help you - seek out a compounding pharmacist (try an apothecary - apothecaries and pharmacies are often interchanged as though they are the same thing (sometimes they are, its just the name the business chose) but MOST apothecaries are compounding pharmacists).

2) you will require a prescription - your family doctor should be able to provide this for you however our family doctor didn't know too much about it so didn't really know what to prescribe dose wise etc. I went to the Apothecary first, discussed it with a very knowledgable compounding pharmacist and he looked over the list of medications my mother is on, discussed with me how DCA works and confirmed that it has in fact been used for 25 years in treating cancer in humans with success, and figured out the dose for me. He then called my doctor (whom he knew) and told the doctor what needed to be put on the prescription.

3) Finally, the compounding pharmacist told me that DCA works best in combination with chemotherapy. (although it is important to discuss the medication you are on with the pharmacist including the chemotherapy because I don't know if it works well with ALL chemos, I just know that in my mothers case, he thought it would work best together, (and that is how it has been used by a particular doctor in the USA for 25 years).

Of course, the other issue is that the pharmacists who carry the stuff, are having a difficult time keeping it stocked because there is so much interest since the University of Alberta article. The pharmacist I used has just a small supply on hand now but is waiting for a larger shipment to come in from the UK but it may be a month or so. But even so, I strongly urge you to get it through a prescription and a reputable compounding pharmacist - you can not be sure exactly what you are getting if you just order it over the internet - it may not even be DCA and it could be harmful to you, and even if it is DCA, you can't be certain of the grade or purity and then you can't possibly know what dose to use. If the pharmacist advises he doesn't have any at the moment and you can't wait for him to get it in, try and find another pharmacist who does have it in stock.

All the best to everyone in your search, and I pray it turns out to be as promising and effective as we are all hoping!

Thanks for your informative posts!

Dr. Burzynski uses Antineoplaston Therapy. These are peptides and amino acid derivatives. These are many clinical trials, using this cancer drug, in process right now.

He does not use DCA but his drug seems to work, in the end, the same. Here is a paragraph explaining it's effect on cancer.

Antineoplastons act as molecular switches, which turn off life processes in abnormal cells and force them to die through apoptosis (programmed death of a cell). While they trigger the death of cancer cells, they do not inhibit normal cell growth. They specifically target cancer cells without harming healthy cells.

It is generally known that the cancerous process results from increased activity of oncogenes and decreased expression of tumor suppressor genes. Antineoplastons “turn on” tumor suppressor genes and “turn off” oncogenes restoring the proper balance in gene expression

g_generis@hotmail.com

Could we start two more lists.

1.Towns that have prescribing Dr's. (names can be or not included)
2.Towns with compounding labs supplying prescription customers.

Thank you Heather.
Diana

You can start a thread here if you wish on where DCA is being prescribed, but since I can't verify suppliers, I don't want to be held responsible for them.

Thanks,
Heather, Forum Moderator

My name is Pierre and I reside in Toronto.
My father has cancer and will soon start chemo .

My father lives in Montreal.

Can I get a prescription from Quebec and have an Ontario pharmacist supply me with the DCA.

Can you let me know who your supplier of DCA is?

You can reply at my email address.

pfortin@forrec.com

Thanks,

Pierre

I, too, live in Ontario (Niagara) and I'm looking for a source of DCA - could you email me the name and address of your supplier please.... waf@iaw.on.ca

Thanks

You mentioned that your pharmacist gets supplies of DCA from the UK. I live in the UK and would be very interested to find out a UK supplier. Do you think your pharmacist could advise me ?

Thanks

Geoff

chk them out...

Good luck to u!

Ciao
"Z"

Ranjit.

Ranjit (hope you don't mind me answering your question)

DCA is sodium dichloroacetate. You can also buy pharmaceutical grade quality from www.buyDCA.com

Take care,
Sandra

Hi Aurora,
What I meant is that what we have been refering to as DCA (for the purpose of discussion on this forum) is actually sodium dichloroacetate, NaDCA. (The chemical symbol for sodium is Na).

Thanks,
Sandra

O

Here it is again:

J.E. Pierce Apothecary
Brookline, MA

Phone Number:
1-617-566-4080 (ask for Steve, the pharmacist).

You need to make payment arrangements and probably can fax your prescription to them.
Good luck. This might also be a good place to get your Thiamine supplement.

http://www.thedcasite.com/dcaforum/DCForumID2/2.html#27

all info is provided on my brothers cancer.

We now need to get some sodium DCA to start using it I want to thank you for providing some information.

I just hope that getting DCA will not be too dificult.

God Bless all.

That info was taken down, and it not avaible? Does that mean it will not be available here now?

I called everywhere, and it's a month away. I doublt, my mother can last that long. The past two days now, she can only drink 8 ounces of protien drinks a day now, and last night she can barely drink 16.

In the name of God, can anyone share a 3 day supplie to get her started?

Steve

SteveDobson@prodigy.net

THANK YOU SO MUCH!!!

huge hugs and kisses coming your way

Is it the real thing? I sure don't want to add to my wife's condition but this is darn tempting... Any negative side effects from somebody who's tried their stuff?

Thank you so much! This is a fantastic site for people with little hope left...

Alain

Phone Number:
1-617-566-4080 (ask for Steve, the pharmacist).

You need to make payment arrangements and probably can fax your prescription to them.
Good luck. This might also be a good place to get your Thiamine supplement.

"Dichloroacetic Acid Sodium Salt 2156-56-1"

2156-56-1 is the "CAS#" for NaDCA so this is the correct one.

Tel: 1-780-422-1397 Ron, Pharmacist

I just spoke to a pharm assistant at "Market Drugs Medical" in Edmonton. Ron is the pharmacist and he won't be in until Monday. Apparently they have 6 pharmacists hunting hard for another supply.

Good News:
I asked if there were a lot of people getting prescriptions and he said yes, from Edmonton, Victoria, Vancouver, and Ontario. There were other areas, but it seems these communities must have some doctor who is prescribing.

No News:
I tried to find out which doctors were prescribing but he could not say, but he said that he hasn't had a prescription from BC. So if you talk to them---and you want to know if there is a doctor in your area, just ask if anyone is getting a prescription from your town, then put an add in your local paper. (Maybe we should all do that.)

Bad News:
Well, none at all-no negative feedback, but also no positive feedback. Some people are getting DCA from this pharm. and they need to have their prescriptions filled so the bad news is that this NA DCA supply has dried up. I asked if there was any feedback or cancelation of their prescriptions and I guess there hasn't been. He said they had a huge waiting list.

=---------------------------------==-=-=--=-=-=-=-=-=-=-=-=-=

>Try Market Drugs Medical in Edmonton, Alberta. You will
>require a prescription from a medical doctor. Ron is the
>pharmacist and he can be reached at 780-422-1397. The cost
>is approx. $2.00 per 500 milligram capsule.

If we have a Doctor on this website, he should be able to prescribe? No?

Unfortunately,in order to suppy a prescription we must see the patient, test results etc. There also are restrictions with respect to sending medications from Canada to the US.

Each patient should be able to get a script from their MD and forward it on to Market Drugs if they in fact have a supply.

It would be helpful if anyone who is aware of a source of supply would post it or send information directly to me at mcr7777@telus.net and I will post it.

I have sent an email to you for a request for you to see my mother.

Thanks.
Diana

http://www.buydca.com/index.html

Question: Selling Sickness: Big Money for Drug Co. (A.Cassels)

If you use Lipitor or Zocor or Simivastin, you should read Dr. Cassels book on selling sickness.

So, if DCA is the CURE, why doesn't Health Canada immediately take over research? Doesn't Health Canada or even WHO want CANCER eridicated?
Don't we all find this Odd to say the least. Haven't we all got questions deep inside, while seeking DCA?

OR...suppose the countering pressure is coming from multi-trillion dollar profiting pharmaceuticals influencing our Health Care System to not get into DCA for Cancer. If Canada is not willing to research it, it follows that they don't want to reduce the burden on our health care system. So--how much influence does these big lobby groups have in influencing our HEALTH, WELLNESS and CURES. Essentially YOU/US, our loved ones, and our world community are left to desparately seek out this cancer treatment, and are willing "unidentified test subjects" for the cure or remission treatment. Please read the articles below?

What do you think?

===========================================
FOREWARD by Diana:

Yesterday I attended the "Selling Sickness" lecture by Allan Cassels, UofVictoria Asst Prof of Drug Policy Research at Thompson Rivers University, Kamloops, BC.

Dr. Cassel spoke about how the Pharm's are not in the business of making people well. (Did anyone see the article I posted that Roche is sponsoring 20 Cancer Infusion Clinics in Canada and I suggest to you its not so Cancer is beaten & Roche will lose customers or put themselves out of business). This is a 1st World Country. Why are we living a Marxian Health Care system??? PHARMs are the company store, and we will always be indebted to them for their treatments but most certainly not cures.

Conversely, the Un.of Alberta and Dr. Mickelasis announce, after studies and getting patents, that DCA may be the Cure for Cancer. What happened before that: Dr. M. and the UoA went into business to attract investors and funding for DCA research, but failing that, the University of Alberta removed itself from DCA Research sponsorship. Why would they do this if there is a potential of being known as the University that found the Cure. We already have an 'Edmonton Protocol' for Diabetes I and islet transfers. Imagine another 'Edmonton Protocol for Cancer'! I have wondered WHY would DCA be announced to the world, and what was the expected reaction? Well for those of us not 'in the know' should wonder why UofA or Dr. Archer or Dr. Mickelisos are not responding to the storm that has come for those seeking a cure for their cancer. One by one, people with cancer are putting themselves on the line due to this announcement. (I think that there were more unofficial studies done, b/c a scientist just doesn't stop when he is near a life-saving break through-don't you agree. In the next reply, see information on Dr. Cassels and SELLING SICKNESS. Another Canadian making a difference.

As another minor point, Dr. Cassels tried to hold a meeting with local Kamloopsian physcians. He had a crowd of 3. However, he later learned that the Pharm companies HOSTED 'drug' suppers at a local ritzy restaurant and this happens weekly. That night's topic was obsity. What drug was flogged? WEEKLY Suppers...doesn't that strike you as 'interesting'. Ask you doctor if he participates and attends these same dinners in your community?

Thanks
diana
g_generis@hotmail.com

(credits)
http://www.commonground.ca/iss/0509170/cg170_donuts.shtml

Alan CASSELS, a drug policy researcher at the University of Victoria, BC CANADA, provides a chilling look at how the world's largest pharmaceutical companies are turning healthy people into patients.

Employing sly marketing campaigns that convince people they have something wrong with them, Big Pharma creates niches for drugs it hopes will become blockbusters.

Critical to the commercial success of these drugs is the cooperation of the doctors who wield the power to write the prescriptions. So it is that billions of warm donuts - and free drug samples - are gifted to doctors and their receptionists across the world, compliments of the drug detailers, the sales reps whose job it is within the pharmaceutical empire to ensure that doctors prescribe these magic bullets to their patients.

Cassels has just co-authored a book called Selling Sickness: How the World's Biggest Pharmaceutical Companies Are Turning Us All Into Patients. See review below.

______________________________

Big pharma: It's enough to make you sick
By ABBY LIPPMAN

Saturday, August 6, 2005 Page D8, Globe and Mail

Selling Sickness:
How the World's Biggest Pharmaceutical Companies
Are Turning Us All Into Patients
By Ray Moynihan and Alan Cassels

GreyStone, 254 pages, $32.95

The pharmaceutical industry is global. It's also powerful and rich.

And lately, it's all over the news. Notices of different drugs pulled off the market (Vioxx) or having to carry "blackbox" warnings for users (SSRIs, DepoProvera) blazon newspapers' front pages. Cheryl Ladd and Kirk Douglas grace the entertainment pages telling us to "ask our doctors" about the medical marvels that helped them or their "loved ones" -- and can also help us -- while Guy Lafleur pushes ##### in the sports section.

Then, in the business section, we read details of the trial of drug-company giant Merck accused of suppressing facts about the dangers (deadly for perhaps thousands) of Vioxx, its medication for
arthritis and acute pain.

We've generally assumed that the pills we take are necessary, that they work and are safe -- and that celebrities are entertainers, not health educators. We expect physicians to prescribe what they know is good for us, and government regulators to safeguard our health. But given all the recent news, could these assumptions be wrong?

Ray Moynihan's and Alan Cassels's Selling Sickness throws light on these taken-for-granteds, revealing some hard truths about pharmaceuticals and those who make, sell, regulate, prescribe and front for them. Drawing on extensive interviews and wide-ranging documents, these long-time, knowledgeable researchers of the pharmaceutical industry develop a chilling story of drug salesmen wining and dining physicians to encourage them to prescribe their newest, priciest product; of companies reporting only studies with favourable results to regulators; of experts heavily funded by drug companies writing clinical guidelines that change the threshold for "abnormality" and establish treatment standards; and
of large sums of (hidden) money given to high-profile celebrities who
help "brand" some product.

The 10 case studies in Selling Sickness illustrate the tactics Pharma
(current shorthand for the entire industry) uses to sell sickness, among them: medicalizing the ordinary (menopause, for example); framing mild symptoms as diseases (shyness morphs into a psychiatric diagnosis); giving social conditions (being "too tired for sex") a medical label ("female sexual dysfunction"); creating "epidemics" by constantly changing diagnostic guidelines (e.g., lowering the bar for treatment of "high" blood pressure or "high" cholesterol).

The extensive details Moynihan and Cassels provide make it all too clear how artificial -- and elastic -- the categories that separate the "normal" from the not-normal are; how little good taking branded pills for many "abnormalities" may actually do; and worse, how much harm these medicines can cause when the research that gets them regulatory approval is, as is often the case, hidden, short-term or biased.

The selling of sickness seems to follow a familiar pattern. A
pharmaceutical company identifies a wedge condition, set of symptoms or "risk factors"; hires a PR firm to come up with a "disease" name,
ideally something catchy with a pronounceable acronym (e.g., SAD);
develops a drug, or adapts an existing one, to tout as a "fix" for this new medical problem; and begins massive marketing to physicians and the public. The media pick up the story, suggesting that the "new" disease is greatly undiagnosed/undertreated; the market expands; drugs sales rise. And voila! Another blockbuster is born.

To read Selling Sickness is to realize that the pervasive and systemic operations of the pharmaceutical industry may be much more dangerous threats to the health of Canadians than the currently demonized waiting lists that delay joint or eye surgery. It's not just one company making a bad drug. Rather, almost an entire industry seems engaged in manipulating our lives, working to make us all patients in need of a cure or, perhaps, just the "not-yet-sick" waiting for some pill to be developed that will fix something we didn't know we had.

As Moynihan and Cassels suggest, Pharma sells sickness mostly to make
money. Whether they sell up front or through patient groups or
celebrities, they can only do this because governments are also taking part, creating the conditions in which diseases can be created and profits made. This probably dates back to the 1980s, when health was labelled a "growth industry" and the Canadian government (along with that of the United States) lowered taxes for corporations, changed patent and advertising laws and regulations in favour of business, and altered how drug reviews are financed so as to speed approvals.

Selling Sickness meets the criteria for being "evidence-based," and has the right credentials: Five of the 10 cases described here were first laid out in the British Medical Journal in 2002.

However, it is not the first book to call attention to the phenomenon captured in the phrase "a pill for every ill," or, perhaps more apt today, "an ill for every pill." More than 20 years ago, women's groups in Canada and the United States raised alarms about the turning of menopause into a "hormone deficiency" state, as well as about the use -- and evident harms -- of insufficiently tested drugs sold to women to prevent miscarriage or pregnancy.

Lessons learned from the women's health movement (then and now) offer
models for how to deal with today's sickness- and drug-sellers. But
Moynihan and Cassels don't sufficiently acknowledge the persisting
gender bias of drug development and the decades-old medicalizing of
women's bodies, even though six of the 10 conditions analyzed in Selling Sickness are conditions experienced by -- and treated more in -- women than men.

This is not coincidence: Women are sold sickness and also use drugs more often than men. Moynihan and Cassels are at their best detailing how selling sickness is happening. But their analytic lens isn't sufficiently wide, so they don't connect their themes to ongoing activities with huge potential to create diseases-in-waiting for drugs of the future (e.g., brain imaging to "see" why we behave as we do, or gene mapping to seek DNA patterns that make us "susceptible" to just about anything). Moreover, while Selling Sickness has abundant references to the actions of the U.S. Food and Drug Administration, the Canadian content sometimes feels more like an "add on" than part of an integrated whole.

A range of well-intentioned proposals is now under consideration in
Canada and elsewhere to rein in some of the worst practices described in Selling Sickness. These include mandatory public registration of all drug trials, mandatory reporting of adverse drug effects and updated requirements for declarations about sources of funding by researchers, "expert" advisers and patient groups. If these come into practice, perhaps they'll alleviate some problems. But by themselves, they can't prevent the growing health burden caused by the continued massive selling of sickness -- and of harmful drugs.

Attaining this will also require tackling upstream driving forces and, for example, changing tax and patent laws to prevent the development of "me too" drugs; excluding entirely those with drug-company ties from decision-making and from regulatory bodies that judge if our medicines are effective and safe; enforcing laws against direct-to-consumer advertising of drugs and outlawing completely the "see your doctor" variety. And maybe even creating a publicly funded independent institute
to do drug trials.

Selling Sickness is an important exposé of many of the dangers of
letting corporate interests determine both who is sick and how to treat them. It shows why we must demand of government a firm, accountable,transparent commitment to ensuring we get the safe and effective medicines we need when we are sick with real diseases. But as always, primary prevention will be even better for our well-being, and this will require social policies that give everyone access to the resources that
protect our health and keep us well.

______________________________

Abby Lippman is a professor of epidemiology at McGill University and
often uses this as a cover for her activism with Women and Health
Protection, where she is on the steering committee, and with the
Canadian Women's Health Network, where she is chairwoman of the board.
close window

I am very puzzled!

Edmonton: xxxx ph.xxxx prescriptions from Vic, Vanc,Edm, Ontario

Campbell River xxx ph.xxx Said to fill prescriptions

Kamloops xxxx ph. xxxx None known yet, will report later if
any pharmacy is or will fill prescript.

Prescribing Doctors (community only for now)

Edmonton Name of Pharm & contact info.

Vancouver

Victoria

small town, Ont.

We need a relational database for this.

diana

When you first enter a conference room such as here:
Conferences/DCA Availability/

At the top of the message list you will see the 'post'.

Click that and start a new title in that conference. If you are reading someones message the 'post' command is missing. Only when you are at the top level of that conference will you see this.

MarkW

Organize information relating to DCA. If you are not able or willing for whatever reason to be part of the research study on DCA that is supposed to be available via U of Alberta in May 2007, then NETWORK & coordinate your use of DCA so that everyone can benefit. Form workgroups (task force)to:

1. Identify source(s) of DCA that are reliable regarding product quality.
2. Create forms (documents) to enable objective assessment of those receiving DCA. Such documents would indicate:
--nature of malignancy,
--prior therapies,
--current disease status,
--other internal medical issues.
--Flow sheets to indicate dates & dose of administration of DCA.
--Flow sheets to also indicate laboratory results to monitor safety of DCA AND parameters to gauge success of treatment (biomarkers, radiology imaging, etc). Such information should be part of a typical study protocol.

3. Create groups to review the above results at regular intervals in order to ensure that crucial info is being collected. DCA must be regarded as a drug with potential side effects until proven otherwise.

4. Enlist dedicated people who wish to make a contribution to the welfare of others & who seek to understand what works & what does not work.

In the ideal situation, local patient & physician groups would be set up to explore the efficacy & toxicity of DCA in pilot studies involving 20-30 patients rather than having mass numbers of people possibly having their cancer therapies misdirected or subjecting themselves to toxicities. Over the years I have seen this happen many times.

I believe the intent of Dr. Michelakis & the group at the U of Alberta in Edmonton is to create such study sites. However, from reading the 45 posts on DCA Discussion Forum, it appears that many of you have loved ones who can not afford to wait for such study sites to be activated. I would still maintain & sincerely wish that each of you who does become involved with DCA should do so in a responsible fashion that adds to our understanding of this small molecule.

Lastly, intend to use this information to publish your results so that others can benefit. Results, positive or negative should be published. If you are going to pursue this, then do so as intelligently as possible. These are only preliminary thoughts & I am sure that a group of motivated & well-read individuals can work together to evolve this further.

Dr. Strum’s idea of physician led study groups is great, but until we can find those professional volunteers let’s begin by creating and sharing as accurate a data-base as possible. What I am imagining is a spreadsheet that will focus all the relevant information (as outlined in Dr. Strum’s message) in one spot on the website.
I would be willing to help coordinate the information, but it would be helpful if a physician would be willing to help me set it up. To do this we would also need support from the admin folks so that we could add that section to the website.
And of course, those of you who have already begun treatment with DCA would need to be willing to share your information.

Let me know what you think.

Susan

My thought was that this should be patient/family led and physicians assisting. I am a firm believer in patient empowerment and the ability of patients-family-physician (in that order) to change the status quo.

>until we can find those professional volunteers let’s begin
>by creating and sharing as accurate a data-base as possible.
>What I am imagining is a spreadsheet that will focus all the
>relevant information (as outlined in Dr. Strum’s message) in
>one spot on the website.

Exactly.

>I would be willing to help coordinate the information, but
>it would be helpful if a physician would be willing to help
>me set it up. To do this we would also need support from the
>admin folks so that we could add that section to the
>website.

I believe we need to see if the website administrators are agreeable to that. If not, it would need to be done via ordinary email communications. I could give some input but I have my hands full with my clinical practice, etc. I would like to see at least 3 or 4 people and ideally one or two physicians involved.

>And of course, those of you who have already begun treatment
>with DCA would need to be willing to share your information.

That would be extremely valuable. To use one of my favorite quotes:

"Our humanity lies in our human unity."

>
>Let me know what you think.

Feedback/involvement/commitment are all foundational to the success of this kind of enterprise. This is how the AIDS patients networked to get active anti-HIV agents to the patient in a record fashion.

This makes sense to me and I am hoping that this online community will be the source of these groups.
>
Creating a database

>I believe we need to see if the website administrators are
>agreeable to that. If not, it would need to be done via
>ordinary email communications. I could give some input but
>I have my hands full with my clinical practice, etc. I
>would like to see at least 3 or 4 people and ideally one or
>two physicians involved.

I will contact the administrators and see if they are willing to add this section to the site. I will also contact those members who are taking DCA and make sure that they are willing to participate.

We are fortunate to have someone with Dr. Strum's experience offering to put in whatever limited time he has available. Are there any other members on this site who are willing to volunteer for this effort? Please let me know.

Susan

.

why re invent the wheel??

Maybe the easiest solution would use Microsoft Office Excel. Make an xls file containing the data and save as an htm/html file.

The result is a web page that contains all the information in the form you saved it in. Maybe the Admins here can provide a place to put it and be accessed by a link in thier main menu.

As new info is added or changed, update the xls file, save as htm and re-upload. (Or send to admin to insert)

Mark

http://groups.yahoo.com/group/fieldsofhope

Then will be in touch with you
Blessings Catherine

Since DCA shuts down glycolysis, it should then be capable of killing cancer stem cells. I read one paper that discussed that DCA might be affecting the adult stem cells that do myelin repairs to nerve cells. This would explain the peripheral neuropathy, but its also a good clue that it would kill cancer stem cells. They are the ones that come back. Traditional chemo is toxic to them but often it can't be taken for a long enough period to kill them. Especially with the mitochondria,, and so the P-53 suicide system not working due to the cancer.

Cancer is an embyonic stem cell that fails to mature , then is reawakened later in adult life. Its not genetics either, but due to "epigenetic causes" both the silencing of the embryonic stem cell and its reawakening are epigenetic per Laird Nature Genetics

Cancer is an embyonic stem cell or an adult stem cell that has reverted to an embryonic state Jan 2006 Gostjeva et al (MIT) paper on bell shaped nuclei, where she compared a colon embryonic stem cell vs an adult colon cancer stem cell. They were identical, each making the same 7 cell types.

President Bush, SAVE YOUR PEOPLE, FUND THE SCIENCE AND THE TRIALS!!!!!

"Google Docs & Spreadsheets is a free web-based word processing and spreadsheet program that keeps documents current and lets the people you choose update files from their own computers."

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