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DCA Discussion Forum
Sandra
Member since Feb-27-07
340 posts |
Apr-24-07, 04:55 AM (PST) |
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"Side Effects - Helpful Information"
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I've been seeing many posts lately about side effects that are occurring, but ones that are not likely caused by DCA directly. From the toxicology articles, DCA's most common side effect is peripheral neuropathy. People have been experiencing mental side effects that I believe are attributable to TUMOR LYSIS SYNDROME. Here are two very good links explaining that. http://en.wikipedia.org/wiki/Tumor_lysis_syndrome http://www.answers.com/topic/tumor-lysis-syndrome I personally believe I've been experiencing hypocalcemia related to tumor lysis. I have many of the symptoms. I've been reducing my dose of DCA, and will have blood work in the near future to confirm this. And I'll be speaking with my doctor to determine a course of action to ameliorate this. If you are experiencing symptoms of tumor lysis, please take a few days off DCA until you are feeling better and consult a doctor if possible to have your electrolytes checked. Take care, Sandra |
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- RE: Side Effects - Helpful Information,
Sandra, Apr-24-07, 06:20 PM, (1)
- RE: Side Effects - Helpful Information,
Naseela
, Apr-24-07, 06:41 PM, (2)
- RE: Side Effects - Helpful Information,
Sandra, Apr-24-07, 07:13 PM, (3)
- RE: Side Effects - Helpful Information,
Sandra, Apr-24-07, 07:17 PM, (4)
- RE: Side Effects - Helpful Information,
Sandra, Apr-24-07, 07:32 PM, (5)
- RE: Side Effects - Helpful Information,
Sandra, Apr-25-07, 00:24 AM, (6)
- RE: Side Effects - Helpful Information,
Burt
, Apr-26-07, 01:52 AM, (7)
- RE: Side Effects - Helpful Information,
Sandra, Apr-28-07, 02:45 AM, (11)
- RE: Side Effects - Helpful Information,
bobmcpherson, Apr-28-07, 09:07 PM, (12)
- RE: Side Effects - Helpful Information,
Lieve, Apr-30-07, 07:00 PM, (14)
- RE: Side Effects - Helpful Information,
Lieve, May-13-07, 09:24 PM, (19)
- RE: Side Effects - Helpful Information,
Geri, May-20-07, 08:58 PM, (26)
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Sandra
Member since Feb-27-07
340 posts |
Apr-24-07, 06:20 PM (PST) |
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1. "RE: Side Effects - Helpful Information"
In response to message #0
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Okay, I have a list of blood work I'm having done to monitor for tumor lysis: Under Hematology -CBC Under General Chemistry -GLU (glucose random) -NA -K -CL -CO2 -CRE -CA -PO4 -MG -TP -ALB -ALP -UA -TBIL -GGT From what I'm experiencing, it seems a balance must be struck between tumor action and general health. That is, don't take so much DCA that you feel sick - because tumor lysis can be very dangerous (even causing life threatening renal failure). DRINK PLENTY OF WATER to flush debris from your system. There are so many people that I care about on this forum. PLEASE be responsible, and listen to your body! But I also have to say I'm VERY EXCITED THAT DCA IS CAUSING MY TUMOR TO DIE! THIS IS AMAZING! |
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Naseela

unregistered user
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Apr-24-07, 06:41 PM (PST) |
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2. "RE: Side Effects - Helpful Information"
In response to message #1
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Sandra, I have been reading most of the info on the DCA site. I have a personal reason for it. My sister(38) has terminal breast cancer that spread to lungs and the brain. She is paralysed and not talking and we have no idea how much cognition she has of the world around her. We started her on DCA about 17 days ago. I wanted to report if anything significant happened. But two days ago, she was taken to the intensive care for a huge drop in blood pressure. The doctors did not know why, but she got stable after adminisetring (I think salts). She is not here, she is in Yemen, where she is in a hospital being taken care of doctors and my family. The doctors are very cooperative about the DCA and any other thing my family propose. When I read your email about tumor lysis. I thought that may be an explanation of what happened to her. Before this last incident, she seemed to have the obvious tumors regressing on her chest (it's ulcerating tumors). And her general health seems to be better including her cognition. What do you mean by the blood test you have been doing to check for tumor lysis. what do you look for? Thank you, and I wish you and everybody well in their fight.Naseela I wish you well. |
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Burt

unregistered user
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Apr-26-07, 01:52 AM (PST) |
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7. "RE: Side Effects - Helpful Information"
In response to message #1
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Hi Sandra, I am glad to hear that you appear to be doing so well on DCA and your other, various, supplements. I was just wondering if you have had any objective, measureable tests that indicate tumor shrinkage. I do believe that, at one time, you were having difficulty getting CT-scans arranged through your doctor. Have you had a scan? And did it show tumor shrinkage? You appear to believe that your cancer is being defeated and I am just wondering what you are basing that on. All the best in your continuing struggle. My prayers are with you. Burt |
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Interested

unregistered user
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Apr-26-07, 08:28 PM (PST) |
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9. "RE: Side Effects - Helpful Information"
In response to message #8
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(Sandra, you're a brave, and incredible person.) What made you choose the DCA avenue May not have been written. But for those left without choices, And for those without medical insurance, For those without money, but a loving spouse, Child, Mother, Father, Brother, Sister. Those facing death but hopefully LIFE with dignity, For those hoping to leave something behind, To their loved ones, children, While attempting to financially, Emotionally and physically cling to life, And fight a gruesome, wicked disease, All at the same time. YOU, Sandra, are an inspiration. You've helped offer hope for the hopeless. A light in the dark, a pathway for the poor. For all others here, who along with Sandra, Have seen their life's worth of suffering, Who've endured the suffering of those loved, Who've struggled with this evil disease, And for those of you who are sacrificing, risking, Sharing, worrying, hoping, loving, and working To nearly blindly, find a cure for the rest, How can you be thanked? For all you've done, for your trials, Will your names be remembered? Should all the angels gather one day, And whisper of the ones with selfless courage, And lacking in greed, while wishing good health For perfect strangers, while dedicating one's very self, I'm sure Sandra, and John, And Omega and a few others here, Will be those names who Remain in conversations of angels. You Really Do Care! Time will tell whether DCA is a cure, Or hope for a cure, with correct supplements. Like those brave ones throughout history, Who have lived life on the fringes of threatening frontiers, The people of this site Are very possibly staging the future In a much larger way than any of them imagine. WIth Very Best Wishes, And Hope for Success in Monumental Proportions, May The Great Creator Strengthen Human Hope, Bolster Human Courage, And Deliver Liberating and Divine Cures. Please believe many are hopeful and meditating daily with prayers For your success, speedy recovery to health and happiness. For your wisdom and knowledge to grow and tackle the problems at hand. And for success in all future endeavors. It's time for "GOOD" to win. |
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Sandra
Member since Feb-27-07
340 posts |
Apr-28-07, 02:45 AM (PST) |
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11. "RE: Side Effects - Helpful Information"
In response to message #0
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Here is another abstract: "Tumor Lysis Syndrome as a Contributory Factor to the Development of Reversible Posterior Leukoencephalopathy Abstract INTRODUCTION Reversible posterior leukoencephalopathy syndrome (RPLS) is a recently described clinical and radiological entity comprising headache, seizures, altered level of consciousness and visual disturbances in association with transient posterior cerebral white-matter abnormalities. METHOD We report a young woman with Burkitt’s lymphoma who developed RPLS after combined chemotherapy administered during the tumor lysis syndrome. RESULTS The symptoms in this patient fitted well with those of RPLS; they included ABRUPT ALTERATIONS IN MENTAL STATUS, SEIZURES, HEADACHE, VISUAL CHANGES AND CHARACTERISTIC NEURORADIOLOGICAL FINDINGS. She was given further combination chemotherapy without any neurological complications, at which time she had already recovered from both RPLS and tumor lysis syndrome. CONCLUSION Although many etiological factors have been reported in the development of RPLS, the underlying mechanism is not yet well understood. With prompt and appropriate management, RPLS is USUALLY REVERSIBLE, and chemotherapy can be continued after complete recovery from RPLS. We suggest that TUMOR LYSIS SYNDROME SHOULD BE CONSIDERED AS A CONTRIBUTORY FACTOR TO THE DEVELOPMENT OF RPLS in patients for whom treatment with combined chemotherapy for hematological malignancies is planned." http://www.springerlink.com/content/f125r67796lq7573/
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bobmcpherson
Member since Feb-28-07
3 posts |
Apr-28-07, 09:07 PM (PST) |
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12. "RE: Side Effects - Helpful Information"
In response to message #0
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Dear Sandra, It is my wife, Geraldine who is suffering from Non-Hodgkin's Lymphoma, and her syptoms do look similar to the symptoms of tumour lysis. However, her electrolytes were exactly reversed: Hyper-calcemia, hypo-phosphate/potassium. It would be nice, if her dementia were evidence of the DCA working, but, I am afraid, it is not. She received many infusions of K+ and PO4--- and was given some leachate to reduce her concentration of Ca++. She is home, now, still weak, but not nearly so confused. Unless there is some way that the reverse is also evidence of lysis, then I am left with the cancer in Gerri. Thanks for thinking of us, Bob McPherson |
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John A
Member since Mar-18-07
101 posts |
Apr-30-07, 12:04 PM (PST) |
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13. "RE: Side Effects - Helpful Information"
In response to message #12
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>Dear Sandra, > >It is my wife, Geraldine who is suffering from Non-Hodgkin's >Lymphoma, and her syptoms do look similar to the symptoms of >tumour lysis. However, her electrolytes were exactly >reversed: Hyper-calcemia, hypo-phosphate/potassium. It >would be nice, if her dementia were evidence of the DCA >working, but, I am afraid, it is not. She received many >infusions of K+ and PO4--- and was given some leachate to >reduce her concentration of Ca++. She is home, now, still >weak, but not nearly so confused. Unless there is some way >that the reverse is also evidence of lysis, then I am left >with the cancer in Gerri. > >Thanks for thinking of us, > >Bob McPherson Hello Bob, I have been looking at the chemistry of Tumour Lysis. The literature particularly notes release of Uric acid, calcium and phosphate as Cancer cells breakdown. I am sure that there are other breakdown products which are not as well documented. Firstly considering Uric Acid it has greatly reduced solubility if the body fluids particularly urine is acidic pH below 6.5 for example.The precipitation noccurs in the Kidneys causing restricted filtration and build up of excessive salts such as calcium in the body which would normally be excreted through the urine. This Uric acid blockage is normally corrected by making the urine more alkaline. In a hospital situation this might be by infusion of sodium bicarbonate. On the other hand if the patient urine is too alkaline say pH over 6.8 Calcium Phosphate can precitate in the urine and could lead to excessive Calcium losses unless dietary Calcium exceed the loss due to the Phosphate precipitation of the calcium. If the calcium is very much in excess Calcium Phosphate salts can precipitate at lower pH levels that 6.8 and create Hypo-Phosphate levels.
The Hypercalcium condition described at first pass may be due to an excessive body fluid acidity which has resulted in Uric acid precipitation in the kidneys. Check Saliva and Urine pH levels and if lower than 6.8 this can be corrected.
Adjusting the Urine pH levels to 7.0 may solve all these problems.
Do you have any other Blood test results to share which also indicate kidney / renal problems. Keep us briefed and we will try and work through this together. Best Regards John A. Research Chemist John A |
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Lieve
Member since Apr-23-07
11 posts |
Apr-30-07, 07:00 PM (PST) |
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14. "RE: Side Effects - Helpful Information"
In response to message #0
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Thank you Sandra for that information, I'm prepared now. You know a lot. Maybe you know something else, I look that many people take OXY E, in Belgium we can't buy it, its forbidden, but my husbands doctor give him OZONE (now it is also forbidden), is it the same or not?Thank you and take care. Lieve. Lieve |
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Lieve
Member since Apr-23-07
11 posts |
May-13-07, 09:24 PM (PST) |
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19. "RE: Side Effects - Helpful Information"
In response to message #0
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Hello Sandra, I think my husband is over the tumor lysis syndrome, and he don't take his pain-medicine anymore, just a few times a day a very light medicine, but he is staying loose weight, he eat vegetable, nuts, biogarde and flex seed oil. Now I will give him "Full Blown Carp Complex", but is n' it feed his cancer? I don't find anything about that in my own language, and my English is not good enough. I hope you can help me again. Thank in advance. Lieve |
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Sandra
Member since Feb-27-07
340 posts |
May-13-07, 10:25 PM (PST) |
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20. "RE: Side Effects - Helpful Information"
In response to message #19
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>Hello Sandra, > >I think my husband is over the tumor lysis syndrome, and he >don't take his pain-medicine anymore, just a few times a day >a very light medicine, but he is staying loose weight, he >eat vegetable, nuts, biogarde and flex seed oil. Now I will >give him "Full Blown Carp Complex", but is n' it feed his >cancer? I don't find anything about that in my own >language, and my English is not good enough. I hope you can >help me again. > >Thank in advance. Hi Lieve, Sorry, I don't know what "Full Blown Carp Complex" is. Cottage cheese would be good, and protein powder made from whey or brown rice or hemp seed. What language do you speak? Maybe someone else can help with translating. You can also email me - click the envelope - top right corner. Take care, Sandra
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