the DCA site - Updating you on DCA and Cancer

DCA Discussion Forum

Subject: "Side Effects - Helpful Information"     Previous Topic | Next Topic
Printer-friendly copy     Email this topic to a friend    
Conferences Testimonials ONLY Topic #63
Reading Topic #63
Sandra
Member since Feb-27-07
340 posts
Apr-24-07, 04:55 AM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
"Side Effects - Helpful Information"
 
I've been seeing many posts lately about side effects that are occurring, but ones that are not likely caused by DCA directly. From the toxicology articles, DCA's most common side effect is peripheral neuropathy. People have been experiencing mental side effects that I believe are attributable to TUMOR LYSIS SYNDROME. Here are two very good links explaining that.

http://en.wikipedia.org/wiki/Tumor_lysis_syndrome

http://www.answers.com/topic/tumor-lysis-syndrome

I personally believe I've been experiencing hypocalcemia related to tumor lysis. I have many of the symptoms. I've been reducing my dose of DCA, and will have blood work in the near future to confirm this. And I'll be speaking with my doctor to determine a course of action to ameliorate this. If you are experiencing symptoms of tumor lysis, please take a few days off DCA until you are feeling better and consult a doctor if possible to have your electrolytes checked.

Take care,
Sandra


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top

 
Conferences | Topics | Previous Topic | Next Topic
Sandra
Member since Feb-27-07
340 posts
Apr-24-07, 06:20 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
1. "RE: Side Effects - Helpful Information"
In response to message #0
 
Okay, I have a list of blood work I'm having done to monitor for tumor lysis:

Under Hematology
-CBC

Under General Chemistry
-GLU (glucose random)
-NA
-K
-CL
-CO2
-CRE
-CA
-PO4
-MG
-TP
-ALB
-ALP
-UA
-TBIL
-GGT

From what I'm experiencing, it seems a balance must be struck between tumor action and general health. That is, don't take so much DCA that you feel sick - because tumor lysis can be very dangerous (even causing life threatening renal failure).

DRINK PLENTY OF WATER to flush debris from your system. There are so many people that I care about on this forum. PLEASE be responsible, and listen to your body! But I also have to say I'm VERY EXCITED THAT DCA IS CAUSING MY TUMOR TO DIE! THIS IS AMAZING!


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Naseela
unregistered user
Apr-24-07, 06:41 PM (PST)
 
2. "RE: Side Effects - Helpful Information"
In response to message #1
 
   Sandra,
I have been reading most of the info on the DCA site. I have a personal reason for it. My sister(38) has terminal breast cancer that spread to lungs and the brain. She is paralysed and not talking and we have no idea how much cognition she has of the world around her. We started her on DCA about 17 days ago.
I wanted to report if anything significant happened. But two days ago, she was taken to the intensive care for a huge drop in blood pressure. The doctors did not know why, but she got stable after adminisetring (I think salts).
She is not here, she is in Yemen, where she is in a hospital being taken care of doctors and my family. The doctors are very cooperative about the DCA and any other thing my family propose.
When I read your email about tumor lysis. I thought that may be an explanation of what happened to her.
Before this last incident, she seemed to have the obvious tumors regressing on her chest (it's ulcerating tumors). And her general health seems to be better including her cognition.
What do you mean by the blood test you have been doing to check for tumor lysis. what do you look for?
Thank you, and I wish you and everybody well in their fight.

Naseela
I wish you well.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-24-07, 07:13 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
3. "RE: Side Effects - Helpful Information"
In response to message #2
 
Hi Naseela,

The blood tests are to monitor electrolytes (salts) and other things relating to general health. Talk to your sister's doctor about tumor lysis syndrome. Print some articles for them. I'd suggest taking your sister off DCA until she is stable and then resume at a low dose of 10-15mg/kg/day. Watch for side effects again and if they appear, lower the dose or take her off again for a few days. I think DCA is so effective that we all have to be careful about the side effects of tumor death.

Take care,
Sandra


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-24-07, 07:17 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
4. "RE: Side Effects - Helpful Information"
In response to message #2
 
Here is another article for you.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15063817

Or do a google search on 'Tumor Lysis Syndrome'.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-24-07, 07:32 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
5. "RE: Side Effects - Helpful Information"
In response to message #2
 
One more article using rasburicase 6 mg in the management of tumor lysis syndrome in adults.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=16716134


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-25-07, 00:24 AM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
6. "RE: Side Effects - Helpful Information"
In response to message #1
 
Since I suggested that people drink plenty of water, I thought I should mention it is important with TLS to be sure that what 'goes in' also 'comes out'. There is potential danger of water intoxication if one's kidneys are not working properly. Here are two links:

http://en.wikipedia.org/wiki/Water_intoxication

http://www.alpharubicon.com/med/watertox.html (see table for suggested intake at bottom)

So don't OVERDO it!


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Burt
unregistered user
Apr-26-07, 01:52 AM (PST)
 
7. "RE: Side Effects - Helpful Information"
In response to message #1
 
   Hi Sandra,
I am glad to hear that you appear to be doing so well on DCA and your other, various, supplements. I was just wondering if you have had any objective, measureable tests that indicate tumor shrinkage. I do believe that, at one time, you were having difficulty getting CT-scans arranged through your doctor. Have you had a scan? And did it show tumor shrinkage? You appear to believe that your cancer is being defeated and I am just wondering what you are basing that on.
All the best in your continuing struggle. My prayers are with you.
Burt


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-26-07, 02:25 AM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
8. "RE: Side Effects - Helpful Information"
In response to message #7
 
Hi Burt,
To answer your questions, no I've not yet had an MRI, but my tumor is near enough to the surface that I'm able to measure it in one plane reasonably accurately. The shrinkage is significant enough for me to be certain of it. And the side effects I've been having lately indicate that my body is struggling to dispose of dead tumor debris. I have an engineering background, so I'm all about having real measureable data. I understand your questions and I believe I have hard evidence, even without an MRI.

I'd again like to caution people who are experiencing symptoms of TUMOR LYSIS SYNDROME to reduce their dose of DCA and get blood work done ASAP. THIS IS POTENTIALLY A LIFE THREATENING CONDITION! Please read the links on TLS in my post at the top of this thread. DCA may work SO effectively that the body may not be able to clear tumor debris fast enough.

Thanks for your prayers Burt. I wish everyone the best in their struggle to beat this disease.

TAKE CARE,
Sandra


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Interested
unregistered user
Apr-26-07, 08:28 PM (PST)
 
9. "RE: Side Effects - Helpful Information"
In response to message #8
 
   (Sandra, you're a brave, and incredible person.)

What made you choose the DCA avenue
May not have been written.
But for those left without choices,
And for those without medical insurance,
For those without money, but a loving spouse,
Child, Mother, Father, Brother, Sister.
Those facing death but hopefully LIFE with dignity,
For those hoping to leave something behind,
To their loved ones, children,
While attempting to financially,
Emotionally and physically cling to life,
And fight a gruesome, wicked disease,
All at the same time.
YOU, Sandra, are an inspiration.
You've helped offer hope for the hopeless.
A light in the dark, a pathway for the poor.
For all others here, who along with Sandra,
Have seen their life's worth of suffering,
Who've endured the suffering of those loved,
Who've struggled with this evil disease,
And for those of you who are sacrificing, risking,
Sharing, worrying, hoping, loving, and working
To nearly blindly, find a cure for the rest,
How can you be thanked?
For all you've done, for your trials,
Will your names be remembered?

Should all the angels gather one day,
And whisper of the ones with selfless courage,
And lacking in greed, while wishing good health
For perfect strangers, while dedicating one's very self,
I'm sure Sandra, and John,
And Omega and a few others here,
Will be those names who
Remain in conversations of angels.
You Really Do Care!
Time will tell whether DCA is a cure,
Or hope for a cure, with correct supplements.
Like those brave ones throughout history,
Who have lived life on the fringes of threatening frontiers,
The people of this site
Are very possibly staging the future
In a much larger way than any of them imagine.

WIth Very Best Wishes,
And Hope for Success in Monumental Proportions,
May The Great Creator
Strengthen Human Hope,
Bolster Human Courage,
And Deliver Liberating and Divine Cures.

Please believe many are hopeful and meditating daily with prayers
For your success, speedy recovery to health and happiness.
For your wisdom and knowledge to grow and tackle the problems at hand.
And for success in all future endeavors.
It's time for "GOOD" to win.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-26-07, 08:44 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
10. "RE: Side Effects - Helpful Information"
In response to message #9
 
Wow! I'm in tears. Thank you! I'm a firm believer that God can bring about good from something evil. It's because of my faith in Him that I pour myself into this effort. May all the glory go to Him.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-28-07, 02:45 AM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
11. "RE: Side Effects - Helpful Information"
In response to message #0
 
Here is another abstract:

"Tumor Lysis Syndrome as a Contributory Factor to the Development of Reversible Posterior Leukoencephalopathy

Abstract
INTRODUCTION Reversible posterior leukoencephalopathy syndrome (RPLS) is a recently described clinical and radiological entity comprising headache, seizures, altered level of consciousness and visual disturbances in association with transient posterior cerebral white-matter abnormalities.

METHOD We report a young woman with Burkitt’s lymphoma who developed RPLS after combined chemotherapy administered during the tumor lysis syndrome.

RESULTS The symptoms in this patient fitted well with those of RPLS; they included ABRUPT ALTERATIONS IN MENTAL STATUS, SEIZURES, HEADACHE, VISUAL CHANGES AND CHARACTERISTIC NEURORADIOLOGICAL FINDINGS. She was given further combination chemotherapy without any neurological complications, at which time she had already recovered from both RPLS and tumor lysis syndrome.

CONCLUSION Although many etiological factors have been reported in the development of RPLS, the underlying mechanism is not yet well understood. With prompt and appropriate management, RPLS is USUALLY REVERSIBLE, and chemotherapy can be continued after complete recovery from RPLS. We suggest that TUMOR LYSIS SYNDROME SHOULD BE CONSIDERED AS A CONTRIBUTORY FACTOR TO THE DEVELOPMENT OF RPLS in patients for whom treatment with combined chemotherapy for hematological malignancies is planned."

http://www.springerlink.com/content/f125r67796lq7573/


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
bobmcpherson
Member since Feb-28-07
3 posts
Apr-28-07, 09:07 PM (PST)
Click to EMail bobmcpherson Click to send private message to bobmcpherson Click to view user profileClick to add this user to your buddy list  
12. "RE: Side Effects - Helpful Information"
In response to message #0
 
   Dear Sandra,

It is my wife, Geraldine who is suffering from Non-Hodgkin's Lymphoma, and her syptoms do look similar to the symptoms of tumour lysis. However, her electrolytes were exactly reversed: Hyper-calcemia, hypo-phosphate/potassium. It would be nice, if her dementia were evidence of the DCA working, but, I am afraid, it is not. She received many infusions of K+ and PO4--- and was given some leachate to reduce her concentration of Ca++. She is home, now, still weak, but not nearly so confused. Unless there is some way that the reverse is also evidence of lysis, then I am left with the cancer in Gerri.

Thanks for thinking of us,

Bob McPherson


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
John A
Member since Mar-18-07
101 posts
Apr-30-07, 12:04 PM (PST)
Click to EMail John%20A Click to send private message to John%20A Click to view user profileClick to add this user to your buddy list  
13. "RE: Side Effects - Helpful Information"
In response to message #12
 
   >Dear Sandra,
>
>It is my wife, Geraldine who is suffering from Non-Hodgkin's
>Lymphoma, and her syptoms do look similar to the symptoms of
>tumour lysis. However, her electrolytes were exactly
>reversed: Hyper-calcemia, hypo-phosphate/potassium. It
>would be nice, if her dementia were evidence of the DCA
>working, but, I am afraid, it is not. She received many
>infusions of K+ and PO4--- and was given some leachate to
>reduce her concentration of Ca++. She is home, now, still
>weak, but not nearly so confused. Unless there is some way
>that the reverse is also evidence of lysis, then I am left
>with the cancer in Gerri.
>
>Thanks for thinking of us,
>
>Bob McPherson

Hello Bob,

I have been looking at the chemistry of Tumour Lysis.
The literature particularly notes release of Uric acid, calcium and phosphate as Cancer cells breakdown. I am sure that there are other breakdown products which are not as well documented.

Firstly considering Uric Acid it has greatly reduced solubility if the body fluids particularly urine is acidic pH below 6.5 for example.The precipitation noccurs in the Kidneys causing restricted filtration and build up of excessive salts such as calcium in the body which would normally be excreted through the urine.

This Uric acid blockage is normally corrected by making the urine more alkaline. In a hospital situation this might be by infusion of sodium bicarbonate.


On the other hand if the patient urine is too alkaline say pH over 6.8 Calcium Phosphate can precitate in the urine and could lead to excessive Calcium losses unless dietary Calcium exceed the loss due to the Phosphate precipitation of the calcium. If the calcium is very much in excess Calcium Phosphate salts can precipitate at lower pH levels that 6.8 and create Hypo-Phosphate levels.


The Hypercalcium condition described at first pass may be due to an excessive body fluid acidity which has resulted in Uric acid precipitation in the kidneys. Check Saliva and Urine pH levels and if lower than 6.8 this can be corrected.


Adjusting the Urine pH levels to 7.0 may solve all these problems.

Do you have any other Blood test results to share which also indicate kidney / renal problems.

Keep us briefed and we will try and work through this together.

Best Regards

John A.
Research Chemist

John A


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Lieve
Member since Apr-23-07
11 posts
Apr-30-07, 07:00 PM (PST)
Click to EMail Lieve Click to send private message to Lieve Click to view user profileClick to add this user to your buddy list  
14. "RE: Side Effects - Helpful Information"
In response to message #0
 
   Thank you Sandra for that information, I'm prepared now.
You know a lot. Maybe you know something else, I look that many people take OXY E, in Belgium we can't buy it, its forbidden, but my husbands doctor give him OZONE (now it is also forbidden), is it the same or not?

Thank you and take care.

Lieve.

Lieve


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
Apr-30-07, 08:47 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
15. "RE: Side Effects - Helpful Information"
In response to message #14
 
Ozone is 3 oxygen molecules bonded together, so they are not the same product, but I believe they are both trying to achieve the same thing - better cellular oxygenation. (Cancer cells hate this).

Here's a link to Oxy E
http://www.zeolitesupport.com/cellular-zeolite/catalog/Oxy-E-Cellular-Oxygen-Enhancer-1-bottle-p-26.html

and one for Cell Food, a product that I am familiar with
http://www.luminahealth.com/products/cellfood.htm .


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
sade00
Member since Mar-12-07
4 posts
May-05-07, 03:06 PM (PST)
Click to EMail sade00 Click to send private message to sade00 Click to view user profileClick to add this user to your buddy list  
16. "RE: Side Effects - Helpful Information"
In response to message #15
 
   Hi everyone, my old brother has taken DCA since yesterday, but today he's blood pressure was 140 and 95 which was too high. Before yesterday, he's blood pressure stay normal which was 130. He never had Cardiovascular disease history before.Is there any forum friends who had taken DCA have the same situation with my brother so far?


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
sade00
Member since Mar-12-07
4 posts
May-05-07, 03:17 PM (PST)
Click to EMail sade00 Click to send private message to sade00 Click to view user profileClick to add this user to your buddy list  
17. "RE: Side Effects - Helpful Information"
In response to message #16
 
   Thank you Sandra for your research, that is so useful for me.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
May-05-07, 08:17 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
18. "RE: Side Effects - Helpful Information"
In response to message #16
 
Hi Sade00,
The only thing I can think of is that perhaps your brother has an intolerance to sodium - maybe the potassium DCA would be better for him. Check with his doctors if possible.

I'm humbled and grateful that my cancer experience could help other people. It's extremely exciting for me to think that people's lives are being extended (and their quality of life improved) through the compiled knowledge of members of this forum. It's rewarding to be a part of that and it gives purpose/meaning to my having cancer. Truly, it's my pleasure to help however I can.

And I think we all owe a great debt of gratitude to Jim and his family for making DCA available, especially at the extreme personal expense they have endured - having their motives and reputations questioned in the press. They labor countless hours on all our behalf (behind the scenes) making ALL this possible. Words are SOOO inadequate...but I sincerely believe I owe them my life and I don't know what more I can say than, 'THANK YOU!'

Take care,
Sandra


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Lieve
Member since Apr-23-07
11 posts
May-13-07, 09:24 PM (PST)
Click to EMail Lieve Click to send private message to Lieve Click to view user profileClick to add this user to your buddy list  
19. "RE: Side Effects - Helpful Information"
In response to message #0
 
   Hello Sandra,

I think my husband is over the tumor lysis syndrome, and he don't take his pain-medicine anymore, just a few times a day a very light medicine, but he is staying loose weight, he eat vegetable, nuts, biogarde and flex seed oil. Now I will give him "Full Blown Carp Complex", but is n' it feed his cancer? I don't find anything about that in my own language, and my English is not good enough. I hope you can help me again.

Thank in advance.

Lieve


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Sandra
Member since Feb-27-07
340 posts
May-13-07, 10:25 PM (PST)
Click to EMail Sandra Click to send private message to Sandra Click to view user profileClick to add this user to your buddy list  
20. "RE: Side Effects - Helpful Information"
In response to message #19
 
>Hello Sandra,
>
>I think my husband is over the tumor lysis syndrome, and he
>don't take his pain-medicine anymore, just a few times a day
>a very light medicine, but he is staying loose weight, he
>eat vegetable, nuts, biogarde and flex seed oil. Now I will
>give him "Full Blown Carp Complex", but is n' it feed his
>cancer? I don't find anything about that in my own
>language, and my English is not good enough. I hope you can
>help me again.
>
>Thank in advance.

Hi Lieve,
Sorry, I don't know what "Full Blown Carp Complex" is. Cottage cheese would be good, and protein powder made from whey or brown rice or hemp seed. What language do you speak? Maybe someone else can help with translating. You can also email me - click the envelope - top right corner.
Take care,
Sandra


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
incomingduck
Member since May-4-07
40 posts
May-14-07, 00:37 AM (PST)
Click to add this user to your buddy list  
21. "RE: Side Effects - Helpful Information"
In response to message #20
 
   Maybe she means "full blown carb conplex" such as mentioned on this site which looks like it might be in the Dutch language.

http://www.body-health.nl/shop/HTML/pd-272398930.htm?categoryId=95


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Lieve
Member since Apr-23-07
11 posts
May-15-07, 01:28 AM (PST)
Click to EMail Lieve Click to send private message to Lieve Click to view user profileClick to add this user to your buddy list  
22. "RE: Side Effects - Helpful Information"
In response to message #21
 
   Hello,

Yes, that's what I mean. Is it good for cancer-patients, who loose a lot of weight or is it dangerous for cancer grow?

Lieve


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
billn
Member since Apr-27-07
34 posts
May-15-07, 11:16 AM (PST)
Click to EMail billn Click to send private message to billn Click to view user profileClick to add this user to your buddy list  
23. "RE: Side Effects - Helpful Information"
In response to message #22
 
One theory is that carbohydrates feed cancer, and so a diet that removes carbs completely from the diet effectively starves the cancer of the energy supply it needs.

Billn


  Alert | IP Prin