Clinic prescribes untested cancer 'cure'Toronto MDs' off-label DCA use puts patients, research at risk: experts
(from the last part of the article) "... The couple has now treated or are currently treating a total of 15 patients with DCA. Four have shown significant improvements, says Dr Khan — the rest have either died or seen no improvement.
One of those four patients, a 65-year-old man diagnosed with pleural mesothelioma that has metastasized to the abdomen and the lymph nodes, has seen a lymph node tumour shrink from 6.0x4.2cm to 5.5x3.6cm after four days of high-dose — 45mg/kg per day — DCA therapy. The patient, however, has already been put on DCA twice before and both times had to stop treatment due to side effects. The three other patients — suffering from bone, lung and ovarian cancer respectively — have all seen improvements, Dr Khan says.
Dr Khan is now trying to determine whether a combination of vitamin B1 and alpha-lipoic acid will counteract DCA's neurotoxicity. In the meantime, his clinic continues to take new cancer patients interested in DCA."
http://www.nationalreviewofmedicine.com/issue/2007/06_30/4_patients_practice_12.html