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DCA Discussion Forum
DCA in the news [View All],
DCA News , 01:20 AM, Mar-21-07, (0)
- RE: DCA in the news,
Diana
, Mar-21-07, 11:14 PM, (1)
- A report in NEW SCIENTIST,
DCA News
, Mar-22-07, 11:54 PM, (3)
- RE: DCA in the news,
DCA News
, Mar-23-07, 00:00 AM, (4)
- ClinicalTrials.gov Identifier NCT00015015,
DCA News
, Mar-24-07, 01:14 AM, (10)
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DCA news

unregistered user
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Mar-22-07, 09:33 PM (PST) |
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2. "RE: DCA in the news"
In response to message #1
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>Has the traffic on this site increased since the media has >made it a big issue? Haven't seen an increase in membership, unregistered are difficult to track. Postings haven't increased, if any thing the postings have slowed some. Not sure if this observation is accurate, it just appears to be. Another similar site hasn't had much activity at all. Take care |
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DCA News

unregistered user
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Mar-23-07, 01:20 AM (PST) |
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7. "Conspiracy?"
In response to message #2
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Conspiracy? One thing is for sure, there is a lot of money involved in modern medicine and ALL patients are, as crude as it may sound, “Money Machines” Keep the patient alive as long as possible but don't cure them; Not cost effective to cure! Example is the tobacco companies with legal corruption which has come to light multiple times over the past few years. I'm sure something similar applies to the big pharm companies. Is there a cure for many of the mans ailments? That is a question that has been around for along time. Is it conceivable that big business could do such a horrible thing? Yes, but how can it be proved? The media has already been used to there advantage.................. |
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DCA News

unregistered user
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Mar-22-07, 11:54 PM (PST) |
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3. "A report in NEW SCIENTIST"
In response to message #0
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PROMISING CANCER TREATEMENT TOO CHEAP TO BE WORTHWHILE? A report in NEW SCIENTIST – 20 Jan 2007 – comments on a surprising conundrum – can a cancer treatment be too cheap? It seems that it can. New US research indicates that dichloroacetate (DCA) an odourless, colourless, inexpensive, relatively non-toxic, small molecule could be used as an effective treatment for many forms of cancer. Sadly, because it is not a new drug it cannot be patented and funding for human cancer trials is unlikely to be forthcoming from usual sources. Dr. Evangelos Michelakis, a professor at the University of Alberta Department of Medicine, has shown that dichloroacetate (DCA) causes regression in several cancers, including lung, breast, and brain tumors. Michelakis and his colleagues, including post-doctoral fellow Dr. Sebastian Bonnet, have published the results of their research in the journal CANCER CELL. Scientists and doctors have used DCA for decades to treat children with inborn errors of metabolism due to mitochondrial diseases. Mitochondria, the energy producing units in cells, have been connected with cancer since the 1930s, when researchers first noticed that these organelles dysfunction when cancer is present. Until recently, researchers believed that cancer-affected mitochondria are permanently damaged and that this damage is the result, not the cause, of the cancer. But Michelakis questioned this belief and began testing DCA, which activates a critical mitochondrial enzyme, as a way to "revive" cancer-affected mitochondria. The results astounded him. Michelakis and his colleagues found that DCA normalized the mitochondrial function in many cancers, showing that their function was actively suppressed by the cancer but was not permanently damaged by it. More importantly, they found that the normalization of mitochondrial function resulted in a significant decrease in tumor growth both in test tubes and in animal models. Also, they noted that DCA, unlike most currently used chemotherapies, did not have any effects on normal, non-cancerous tissues. "I think DCA can be selective for cancer because it attacks a fundamental process in cancer development that is unique to cancer cells," Michelakis said. "Cancer cells actively suppress their mitochondria, which alters their metabolism, and this appears to offer cancer cells a significant advantage in growth compared to normal cells, as well as protection from many standard chemotherapies. Because mitochondria regulate cell death--or apoptosis--cancer cells can thus achieve resistance to apoptosis, and this appears to be reversed by DCA." "One of the really exciting things about this compound is that it might be able to treat many different forms of cancer, because all forms of cancer suppress mitochondrial function; in fact, this is why most cancers can be detected by tests like PET (positron emission tomography), which detects the unique metabolic profile of cancer compared to normal cells," added Michelakis, the Canada Research Chair in Pulmonary Hypertension. Another encouraging thing about DCA is that, being so small, it is easily absorbed in the body, and, after oral intake, it can reach areas in the body that other drugs cannot, making it possible to treat brain cancers, for example. Also, because DCA has been used in both healthy people and sick patients with mitochondrial diseases, researchers already know that it is a relatively non-toxic molecule that can be immediately tested in patients with cancer. Source: University of Alberta http://www.depmed.ualberta.ca/dca/ |
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DCA News

unregistered user
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Mar-23-07, 00:09 AM (PST) |
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5. "Kinda makes ya think"
In response to message #4
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Royal Rife: Discovering a Cure for Cancer Can Be Dangerous to Your Health 2000-10-09, WantToKnow.info/Jeff Rense http://www.WantToKnow.info/cancercuresroyalrifeNote: We usually limit ourselves to information which comes from sources known and respected by the public. For this message, we're making an exception. Jeff Rense of rense.com is a radio personality and researcher of major cover-ups with no strong credentials other than a large following of people convinced of the quality of his work. His popular website receives millions of visits a month. Below is vital information everyone should know. Royal Raymond Rife was a brilliant scientist born in 1888 and died in 1971. He received 14 major awards and honors and was given an honorary Doctorate by the University of Heidelberg for his work. By 1933, he had ... constructed the incredibly complex Universal Microscope, which...was capable of magnifying objects 60,000 times their normal size. With this incredible microscope, Rife became the first human being to actually see a live virus. In 1934, the University of Southern California appointed a Special Medical Research Committee to bring terminal cancer patients ... to Rife's San Diego Laboratory and clinic for treatment. The team included doctors and pathologists assigned to examine the patients - if still alive - in 90 days. After the 90 days of treatment, the Committee concluded that 86.5% of the patients had been completely cured. On November 20, 1931, forty-four of the nation's most respected medical authorities honored Royal Rife with a banquet billed as The End To All Diseases. But by 1939, almost all of these distinguished doctors and scientists were denying that they had ever met Rife. The last thing in the world that the pharmaceutical industry wanted was ... a painless therapy that cured ... terminal cancer patients and cost nothing to use but a little electricity. It might give people the idea that they didn't need drugs. Medical journals, supported almost entirely by drug company revenues and controlled by the AMA, refused to publish any paper by anyone on Rife's therapy. Rife technology became public knowledge again in 1986 with the publication of The Cancer Cure That Worked, by Barry Lynes, and other material about Royal Rife and his monumental work. Credits to: http://www.wanttoknow.info/cancercuresnewsarticles |
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Sandra
Member since Feb-27-07
125 posts |
Mar-26-07, 10:56 PM (PST) |
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13. "RE: DCA patent application claims priority from United"
In response to message #9
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A post from IronRyan... http://www.thedcasite.com/dcaforum/DCForumID1/39.html "U of A wasn't even the first one to use DCA in cancer research. If one was to listen to them, it would sound like he is the first person to ever think of it let alone do studies on it. Here are two patents that showed DCA used with lipoic acid where the DCA doubled the rate of tumor kill. United States Patent 6,331,559 Bingham , et al. December 18, 2001 Lipoic acid derivatives and their use in treatment of disease "... This second reagent is preferably an inhibitor of mitochondria energy metabolism and/or one that induces apoptosis. Such reagents include metabolism inhibitory reagents. Many such reagents are known in the art. One particularly preferred reagent is dichloroacetate. This second reagent may be administered sequentially, simultaneously or separately, so as to amplify patient response to said treatment method." and an example in an earlier patent: ..."This was tested in this Example with dichloroacetate (henceforth abbreviated DCA)(8)...." ..."We find that the cells of the experimental subset are killed approximately twice as rapidly as in the control subset."... The experimental subset had DCA while the standard had the lipoic acid by itself. ... So both of these patents I am sure also have studies associated with them that were published. Yet Dr. M doesn't have any of this noted in his work. Maybe he is just weak on research. Or maybe he is hedging his bet for money and fame. I find his inability to recognize earlier research appalling."
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DCA News

unregistered user
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Mar-24-07, 01:14 AM (PST) |
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10. "ClinicalTrials.gov Identifier NCT00015015"
In response to message #0
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Dichloroacetate Kinetics, Metabolism and Toxicology This study has been completed. Study start: December 1994; Study completion: October 2002 Purpose Dichloroacetate (DCA) is a product of water chlorination and a metabolite of certain industrial solvents, thus making it a chemical of environmental concern. However, DCA is also used as an investigational drug for treating various diseases of adults and children, at doses far greater than those to which humans are normally exposed in the environment. Our research involves how DCA is metabolized by healthy adults and by children with a fatal genetic disease, congenital lactic acidosis (CLA) who are treated with DCA.
http://clinicaltrials.gov/show/NCT00015015
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