the DCA site - Updating you on DCA and Cancer

DCA Discussion Forum

Subject: "Use CoQ10 and Niacinamide Instead of Dichloroacetate (D"     Previous Topic | Next Topic
Printer-friendly copy     Email this topic to a friend    
Conferences Topics OTHER Than DCA Topic #615
Reading Topic #615
robmx
Member since May-25-09
63 posts		 Sep-15-10, 05:22 AM (PST)
Click to EMail robmx Click to send private message to robmx Click to add this user to your buddy list  
"Use CoQ10 and Niacinamide Instead of Dichloroacetate (D"
 
   Use CoQ10 and Niacinamide Instead of Dichloroacetate (DCA) to Treat Cancer? – A ‘Crazy’ Theory.

Does this make any sense?

http://thatcrazypharmacist.com/?p=240


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Vitaminboss
Member since Mar-3-07
103 posts		 Oct-17-10, 07:45 AM (PST)
Click to EMail Vitaminboss Click to send private message to Vitaminboss Click to view user profileClick to add this user to your buddy list Click to send message via AOL IM  
1. "RE: Use CoQ10 and Niacinamide Instead of Dichloroacetat"
In response to message #0
 
   LAST EDITED ON Dec-04-10 AT 03:12 PM (PST) by parachute (admin)
 
First of all, Niacinamide, the precursor to NADH (which is sold as a dietary supplement) is also known as Coenzyme 1, which is the major catalyst in most cellular metabolic reactions. Tumors require plenty of NADH to proliferate and biosynthesize ATP (which is also used by the tumor). Secondly, it is only THEORY that all cancer cells are strictly anaerobic, this is FALSE! Only the very aggressive population of cells that have a poor blood/oxygen supply revert to glycolysis (Anaerobic glycolysis) in order to survive, which in turn activates angiogenic factors in order to receive more glucose/fructose. There is a large population of cells which has a great oxygen supply and will only THRIVE in the presence of CoQ10 which is used in cellular respiration (part of the electron transport chain). NADH actually works with CoQ10 and sustains its conversion to CoQH2 (Ubiquinol). They are both TUMOR SUPER FOOD!

This is why the Paw-Paw cell reg protocols (which deplete and shut down tumor ATP synthesis as well as inhibit mitochondrial respiration at complex I) prohibit the use of CoQ10 supplementation and any vitamin catalyst that may increase cell energy while on this treatment (which is pretty effective in tandem with other treatments). The bottom line is, tumors need energy to thrive and NADH & CoQ10 assist in this process.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Jtelecom
Member since Jan-14-11
1 posts		 Jan-14-11, 09:38 PM (PST)
Click to EMail Jtelecom Click to send private message to Jtelecom Click to view user profileClick to add this user to your buddy list  
5. "RE: Use CoQ10 and Niacinamide Instead of Dichloroacetat"
In response to message #1
 
   The assertion that most cancer cells "live" in an aerobic, oxygen-rich environment contradicts the Warburg Effect. The assertion would also negate the usefullness of PET scans, since the cancer cells uptake glucose 200:1 versus normal cells. DCA is thought to work by downregulating glycolysis. It is widely believed that cancer cells have damaged mitochondria, inhibiting the apoptotic cascade of cytokines, etc. A cancer cell is obviously a "damaged" cell. The mitochondria "reads" the cell for damage and proceeds with apoptosis when damage is detected. It stands to reason that substances such as CoQ10 and PQQ(pyrroloquinoline quinone) might be beneficial. The PQQ actually enables the formation of new mitochondrian and the CoQ10 delivers the energy required for respiration, i.e., normal mitochondrial function.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
Vitaminboss
Member since Mar-3-07
103 posts		 Oct-17-10, 07:45 AM (PST)
Click to EMail Vitaminboss Click to send private message to Vitaminboss Click to view user profileClick to add this user to your buddy list Click to send message via AOL IM  
2. "RE: Use CoQ10 and Niacinamide Instead of Dichloroacetat"
In response to message #0
 
   Also, it has been proven that the mitochondria in cancer cells are NOT damaged, but simply not used (in those that run on glycolysis)due to a survival mechanism thats been switched on. Because cancers main goal is not to produce energy like normal cells, but its to proliferate faster, and that does not require much ATP. So trying to feed it more energy catalysts won't accomplish much except by fueling those cells that actually use these enzymes (NADH & CoQ10).

DCA works differently. It works by triggering the apoptotic cascade via the mitochondria by forcing it to activate its cell respiratory function. CoQ10 will never force a non activated mitochondria into working, at least not in those cells that actually use it. Thats the worrisome part with using large doses of endogenous compounds with cancer; Cancer loves it all, and the more you supply, the more it learns to use whatever amount you throw at it. DCA isn't an endogenous compound, therefore, it works.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
robmx
Member since May-25-09
63 posts		 Oct-17-10, 08:07 AM (PST)
Click to EMail robmx Click to send private message to robmx Click to add this user to your buddy list  
3. "RE: Use CoQ10 and Niacinamide Instead of Dichloroacetat"
In response to message #2
 
   Thanks for the reply. Don't understand it but trust in your understanding of it. Didn't sound right to me.


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top
ThatCrazyPharmacist
Member since Dec-3-10
2 posts		 Dec-03-10, 00:17 AM (PST)
Click to EMail ThatCrazyPharmacist Click to send private message to ThatCrazyPharmacist Click to view user profileClick to add this user to your buddy list  
4. "RE: Use CoQ10 and Niacinamide Instead of Dichloroacetat"
In response to message #2
 
   LAST EDITED ON Dec-04-10 AT 03:11 PM (PST) by parachute (admin)
 
Ad hominem attacks do not further our understanding, therefore this post has been redacted.

Thanks,

Parachute
List Admin

Steve


  Alert | IP Printer-friendly page | Edit | Reply | Reply With Quote | Top

Conferences | Topics | Previous Topic | Next Topic