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Vitaminboss
Member since Mar-3-07
92 posts		 Nov-30-08, 08:38 PM (PST)
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"Dihydroartemisinin"
 
   I've read that DHA (Dihydroartemisinin) is more potent than the other analogs, especially involving angiogenesis. Has anyone gotten their hands on this? If so, any word on dosage?


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Dihydroartemisinin [View All], Vitaminboss, 08:38 PM, Nov-30-08, (0)  
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buteyko centre
Member since May-3-07
27 posts		 Dec-02-08, 08:55 PM (PST)
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1. "RE: Dihydroartemisinin"
In response to message #0
 
   http://www.hepalin.com/ these are the guys i bought from great quick service ,many different forms ,


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Vitaminboss
Member since Mar-3-07
92 posts		 Dec-02-08, 11:59 PM (PST)
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2. "RE: Dihydroartemisinin"
In response to message #1
 
   Thats where I buy my artesunate also. They don't carry Dihydroartemisinin. Thats the active metabolite of artemisinin and artesunate. It has shown much higher anti-tumor activity when it is used in this form.


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michele lee
Member since May-26-09
76 posts		 Jul-22-09, 01:37 PM (PST)
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6. "RE: Dihydroartemisinin"
In response to message #2
 
   I'll have to track down the study I read it in, but artensunate metabolizes into dihydroartemisinin, the others don't.


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Sandramoderator
Member since Feb-27-07
807 posts		 Dec-03-08, 07:44 AM (PST)
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3. "RE: Dihydroartemisinin"
In response to message #0
 
I found it available here

100mg $ 95.00
1g $ 199.00

but they say they don't sell for personal use.

http://www.aksci.com/search.asp


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Sandramoderator
Member since Feb-27-07
807 posts		 Dec-03-08, 08:04 AM (PST)
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4. "RE: Dihydroartemisinin"
In response to message #3
 
Wonder if you can ask for a prescription for Artekin or Arterakine - it would have to be off label use though. Malaria is the primary use. Here's a brand new article in Pub Med:

The two fixed-dose combinations of dihydroartemisinin and piperaquine (Artekin(R) and Arterakine(R)) were found to be bioinequivalent in healthy Vietnamese subjects. However, because the Cmax and AUC of dihydroartemisinin and piperaquine were only marginally different between the two formulations similar therapeutic efficacy is expected in the treatment of malaria infections.

http://www.ncbi.nlm.nih.gov/pubmed/19047656?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


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Sandramoderator
Member since Feb-27-07
807 posts		 Dec-03-08, 08:16 AM (PST)
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5. "RE: Dihydroartemisinin"
In response to message #4
 
I couldn't get this page to load, but here's another possibility:
http://www.cotecxin.com/en/products/
Dihydroartemisinin is sold in Africa as Cotecxin in 60 mg tablets, which is manufactured by Zhejiang Holley Nanhu Pharmaceutical Co., Ltd., in China.


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PTB
Member since May-19-08
9 posts		 Jul-24-09, 01:32 PM (PST)
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8. "RE: Dihydroartemisinin"
In response to message #5
 
   Here's another possible source. I've had pretty good luck with ordering directly from Chinese companies. Would not hurt to contact and see if they will sell.

http://www.sciphar.com/Natural/Dihydroartemisinin.asp?gclid=CLLI--ex75sCFRwpawode0Q0-g


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michele lee
Member since May-26-09
76 posts		 Jul-22-09, 01:37 PM (PST)
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7. "RE: Dihydroartemisinin"
In response to message #0
 
  
Here's something. I can't find what I originally read.

"There was a greater than proportional increase in artesunate and DHA exposure with increasing artesunate dose"
Eur J Clin Pharmacol. 2009 Jun 11.


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bastian
Member since Jul-11-09
3 posts		 Aug-23-09, 01:16 AM (PST)
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9. "RE: Dihydroartemisinin"
In response to message #0
 
   Anamed,a charitable organisation, uses a special hybrid - Artemisia annua A-3, to treat malaria and HIV in Africa. The tea contains a lot of Artemisin and other constituents, and it is also used to treat cancer.

The leaves are available as raw material in Europe, but I think in other countries only the seeds are available.

http://anamed.net/English_Home/anamed_artemisia_programme/Artemisia_and_cancer/artemisia_and_cancer.html

http://anamed.net/English_Home/anamed_artemisia_programme/rich_artemisia/rich_artemisia.html


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