Benfotiamine: 24-month, double-blind, randomized, placebo-controlled trial

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    Anonymous

    I'm trying to figure out whether I should add benfotiamine or thiamine to my wife's DCA regimen.  Came across this study on PubMed:

    The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial

    http://www.ncbi.nlm.nih.gov/pubmed/22446172

    RESULTS:

    Fifty-nine patients completed the study. Marked increases in whole-blood concentrations of thiamine and thiamine diphosphate were found in the benfotiamine group (both P < 0.001 vs. placebo). However, no significant differences in changes in peripheral nerve function or soluble inflammatory biomarkers were observed between the groups.

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