For bio-availabilty to be useful you have to get the nanocurcurmin to the target cell and then it has to be effective in the target cell. From the reporting you would have to assume the current researchers are looking at intra-peritoneal insertion or more likely an i.v. route. I don't suppose for a minute they conceive you will be able to sprinkle it on cornflakes.

So i.p. or i.v. deals with efficient transport to the tumour cell doorstep. Then it has to make a target sensitive entry to the tumour cell. If cell entry is universal then an unhealthy ochre stain is likely to spread across the cancer patients of the world. PEG particles *can* be targetted but I not sure anyone is yet routinely doing this in therapy.

Whether nanocurcumin particles will be curatively effective in vivo, even if all the delivery systems work, is not I think really resolved. Activity is reported at the 10 micromolar level. Activity is normally preferred at the nanomolar level otherwise dosings do get quite high.

While I expect you will be permitted to continue to eat most things in raw form (when they have been traditionally available) once they have been prepped so that their sole purpose is therapeutic and not as a food stuff all the normal medical regs will be applied. Requiring i.p. or i.v. insertion just makes that certain.

So functionally there are a bunch of demonstrations to go through before a solid case can be made for using encapsulated curcumin as a commercial cure in the ordinary way. I think it will be yonks before nanocurcumin will be commercially available "off the shelf" and then, if its any good, the medical profession will snaffle it as one of theirs.

The only way round this is to set up your own lab facility now while its unembargoed, make some, and be your own guinea-pig. "Set up your own" is not impossible (it happened here for example) but the facilities required for nanoencapsulation will be somewhat greater - but not impossibly so.

It almost argues for cancer patients clubbing together to set up their own development lab doesn't it? I'm fairly sure that could be made to work legally although not in all legislative domains. A structure providing requested services to its members, delivering only to members, situate off-shore from member domicile etc has many powerful protective mechanisms available - just look at fund managers.

Kind regards - Ian