I am at the end of 48 hours off DCA (as mentioned above) to minimise development of any problems and some things changed:

1. constipation not so bad,

2. eyeballs stopped scratching,

3. continued development of loss of balance (resurrection of old Oxaliplatin neuropathy relating to lower leg reflex arcs).

4. increase in lethargy but also sleeplessness

5. increase in hilar inflammatory state requiring more prednisolone to fix

6. on reflection there is some evidence of restriction of peripheral blood supply other than gum disease, cold feet in particular

7. Oh yes, some of the imbalance mentioned in 3. feels like it might have a CNS component - its worse in some ways than previously and staggers take longer to recover

Kind regards - Ian