I didn't take DCA on 4th June or today. Otherwise I built up quickly to 12.5 mg/kg and kept at that level. I find the experience changes over time. DCA alters my mood positively but that actually morphed into a state of aggression after 10 days.

Perfectly manageable socially but definite sense of short fuse and frustration: this rapidly improves once dosing is deferred. I also found soreness of eyeball. Increased gut disturbance in association with chemo (*severe* constipation).

DCA seems to have modified my chemo experience otherwise for the better: the dreadful depression / low energy I normally get with headache / lassitude / weakness has been greatly improved. The blood tests show some evidence of this - *platelet levels are much improved*. If anybody has any ideas what that might mean do speak up.

The other subjective sensations are not easily interpretable. I do have greater secretion from the lung and some inflammation in hilar regions. I don't think I am taking as much prednisolone to suppress that as usual. I have some discomfort occasionally in other nodes. The liver is generally comfortable and there are no significant symptoms of liver disease.

Oh yes, I also have had a breakout of gum disease in the upper palate in the last 48 hours. It seems to yield to vicious water-picking with mouthwash in the (warm) water. Might be coincidence but could be evidence of reduced peripheral blood supply?

No change in hypertension or heart rate. Some beneficial effect on blood glucose. Weight change due to chemo as expected. Slight extra nausea (normally don't have this) but nothing a chemo patient can't manage. Appetite reasonable given the chemo.

If I think of anything else I'll add it later. Reports www.cybersolver.com/medical

Kind regards - Ian