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Subject: "pH of NaDCA in water?" Archived thread - Read only
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Andrew Yassin
Member since Mar-6-07
13 posts		 Mar-07-07, 10:38 AM (PST)
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"pH of NaDCA in water?"
 
   Hi all!

What is the rough pH of Na-DCA when dissolved in water?
And what are the solubility limits?

I have previously made the mistake to think that NaDCA has a pKa of 1.25; that is wrong. That data is of course for the acid form which is a rather strong acid.

But the actual pH of the sodium salt dissolved in (distilled) water is still important. DCA tends to auto-catalyze its own breakdown rapidly at low pH (Henderson et al, Drug dev Ind Pharm, Vol20(15), p. 2425-37, 1994).

The question is, thus, do one need a buffer?

That relates to solubility - since useful buffers contain plenty of sodium ions.

Please advice!

Regards,
Andrew Yassin


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Omega3
Member since Feb-15-07
21 posts		 Mar-16-07, 05:03 AM (PST)
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1. "RE: pH of NaDCA in water?"
In response to message #0
 
   Ph of NaDCA is 5.0 to 5.2 thus it can be used right out of the bottle


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Cathy Martin
unregistered user
 Mar-23-07, 04:25 AM (PST)
 
2. "RE: pH of NaDCA in water?"
In response to message #1
 
   Hi there,

May I ask how you took the NaDCA? I have been able to obtain some NaDCA in powder form but do not know how to give it to my mum who has breast cancer. Can you mix it with water and drink it? Does it taste nice?

Please email me back on cathy.martin@xtra.co.nz

Kind regards,
Cathy


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